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dc.contributor.authorGurramkonda, Chandrasekhar
dc.contributor.authorPolez, Sulena
dc.contributor.authorSkoko, Natasa
dc.contributor.authorAdnan, Ahmad
dc.contributor.authorGäbel, Thomas
dc.contributor.authorChugh, Dipti
dc.contributor.authorSwaminathan, Sathyamangalam
dc.contributor.authorKhanna, Navin
dc.contributor.authorTisminetzky, Sergio
dc.contributor.authorRinas, Ursula
dc.date.accessioned2011-08-17T13:47:12Z
dc.date.available2011-08-17T13:47:12Z
dc.date.issued2010
dc.identifier.citationApplication of simple fed-batch technique to high-level secretory production of insulin precursor using Pichia pastoris with subsequent purification and conversion to human insulin. 2010, 9:31 Microb. Cell Fact.en
dc.identifier.issn1475-2859
dc.identifier.pmid20462406
dc.identifier.doi10.1186/1475-2859-9-31
dc.identifier.urihttp://hdl.handle.net/10033/139961
dc.description.abstractThe prevalence of diabetes is predicted to rise significantly in the coming decades. A recent analysis projects that by the year 2030 there will be ~366 million diabetics around the world, leading to an increased demand for inexpensive insulin to make this life-saving drug also affordable for resource poor countries.
dc.language.isoenen
dc.subject.meshCloning, Molecularen
dc.subject.meshCulture Mediaen
dc.subject.meshGlycerolen
dc.subject.meshHumansen
dc.subject.meshInsulinen
dc.subject.meshMethanolen
dc.subject.meshPichiaen
dc.subject.meshTechnology, Pharmaceuticalen
dc.titleApplication of simple fed-batch technique to high-level secretory production of insulin precursor using Pichia pastoris with subsequent purification and conversion to human insulin.en
dc.typeArticleen
dc.contributor.departmentHelmholtz Centre for Infection Research, Braunschweig, Germany.en
dc.identifier.journalMicrobial cell factoriesen
refterms.dateFOA2018-06-12T17:55:02Z
html.description.abstractThe prevalence of diabetes is predicted to rise significantly in the coming decades. A recent analysis projects that by the year 2030 there will be ~366 million diabetics around the world, leading to an increased demand for inexpensive insulin to make this life-saving drug also affordable for resource poor countries.


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