Transcriptional profiling of the marine oil-degrading bacterium Alcanivorax borkumensis during growth on n-alkanes.

Sabirova, Julia S; Becker, Anke; Lünsdorf, Heinrich; Nicaud, Jean-Marc; Timmis, Kenneth N; Golyshin, Peter N

dc.contributor.author	Sabirova, Julia S
dc.contributor.author	Becker, Anke
dc.contributor.author	Lünsdorf, Heinrich
dc.contributor.author	Nicaud, Jean-Marc
dc.contributor.author	Timmis, Kenneth N
dc.contributor.author	Golyshin, Peter N
dc.date.accessioned	2011-10-18T08:39:23Z
dc.date.available	2011-10-18T08:39:23Z
dc.date.issued	2011-06
dc.identifier.citation	Transcriptional profiling of the marine oil-degrading bacterium Alcanivorax borkumensis during growth on n-alkanes. 2011, 319 (2):160-8 FEMS Microbiol. Lett.	en
dc.identifier.issn	1574-6968
dc.identifier.pmid	21470299
dc.identifier.doi	10.1111/j.1574-6968.2011.02279.x
dc.identifier.uri	http://hdl.handle.net/10033/145611
dc.description.abstract	The marine oil-degrading bacterium Alcanivorax borkumensis SK2 has attracted significant interest due to its hydrocarbonoclastic lifestyle, its alkane-centered metabolism, and for playing an important ecological role in cleaning up marine oil spills. In this study, we used microarray technology to characterize the transcriptional responses of A. borkumensis to n-hexadecane exposure as opposed to pyruvate, which led to the identification of a total of 220 differentially expressed genes, with 109 genes being upregulated and 111 genes being downregulated. Among the genes upregulated on alkanes are systems predicted to be involved in the terminal oxidation of alkanes, biofilm formation, signal transduction, and regulation.
dc.language.iso	en	en
dc.subject.mesh	Alcanivoraceae	en
dc.subject.mesh	Alkanes	en
dc.subject.mesh	Bacterial Proteins	en
dc.subject.mesh	Biodegradation, Environmental	en
dc.subject.mesh	Gene Expression Profiling	en
dc.subject.mesh	Gene Expression Regulation, Bacterial	en
dc.subject.mesh	Molecular Sequence Data	en
dc.subject.mesh	Seawater	en
dc.subject.mesh	Transcription, Genetic	en
dc.title	Transcriptional profiling of the marine oil-degrading bacterium Alcanivorax borkumensis during growth on n-alkanes.	en
dc.type	Article	en
dc.contributor.department	Department of Bioscience and Bioengineering, Ghent University, Ghent, Belgium. julia.sabirova@ugent.be	en
dc.identifier.journal	FEMS microbiology letters	en
refterms.dateFOA	2012-06-15T00:00:00Z
html.description.abstract	The marine oil-degrading bacterium Alcanivorax borkumensis SK2 has attracted significant interest due to its hydrocarbonoclastic lifestyle, its alkane-centered metabolism, and for playing an important ecological role in cleaning up marine oil spills. In this study, we used microarray technology to characterize the transcriptional responses of A. borkumensis to n-hexadecane exposure as opposed to pyruvate, which led to the identification of a total of 220 differentially expressed genes, with 109 genes being upregulated and 111 genes being downregulated. Among the genes upregulated on alkanes are systems predicted to be involved in the terminal oxidation of alkanes, biofilm formation, signal transduction, and regulation.