The making of filopodia.

Faix, Jan; Rottner, Klemens

dc.contributor.author	Faix, Jan
dc.contributor.author	Rottner, Klemens
dc.date.accessioned	2007-11-16T15:25:43Z
dc.date.available	2007-11-16T15:25:43Z
dc.date.issued	2006-02-01
dc.identifier.citation	Curr. Opin. Cell Biol. 2006, 18(1):18-25	en
dc.identifier.issn	0955-0674
dc.identifier.pmid	16337369
dc.identifier.doi	10.1016/j.ceb.2005.11.002
dc.identifier.uri	http://hdl.handle.net/10033/14602
dc.description.abstract	Filopodia are rod-like cell surface projections filled with bundles of parallel actin filaments. They are found on a variety of cell types and have been ascribed sensory or exploratory functions. Filopodium formation is frequently associated with protrusion of sheet-like actin filament arrays called lamellipodia and membrane ruffles, but, in comparison to these structures, the molecular details underpinning the initiation and maintenance of filopodia are only just beginning to emerge. Recent advances have improved our understanding of the molecular requirements for filopodium protrusion and have yielded insights into the inter-relationships between lamellipodia and filopodia, the two 'sub-compartments' of the protrusive actin cytoskeleton.
dc.format.extent	487397 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.title	The making of filopodia.	en
dc.type	Article	en
dc.format.dig	YES
refterms.dateFOA	2018-06-13T00:31:24Z
html.description.abstract	Filopodia are rod-like cell surface projections filled with bundles of parallel actin filaments. They are found on a variety of cell types and have been ascribed sensory or exploratory functions. Filopodium formation is frequently associated with protrusion of sheet-like actin filament arrays called lamellipodia and membrane ruffles, but, in comparison to these structures, the molecular details underpinning the initiation and maintenance of filopodia are only just beginning to emerge. Recent advances have improved our understanding of the molecular requirements for filopodium protrusion and have yielded insights into the inter-relationships between lamellipodia and filopodia, the two 'sub-compartments' of the protrusive actin cytoskeleton.