The transcription factor FBI-1/OCZF/LRF is expressed in osteoclasts and regulates RANKL-induced osteoclast formation in vitro and in vivo.

Kukita, Akiko; Kukita, Toshio; Nagata, Kengo; Teramachi, Junpei; Li, Yin-Ji; Yoshida, Hiroki; Miyamoto, Hiroshi; Gay, Steffen; Pessler, Frank; Shobuike, Takeo

dc.contributor.author	Kukita, Akiko
dc.contributor.author	Kukita, Toshio
dc.contributor.author	Nagata, Kengo
dc.contributor.author	Teramachi, Junpei
dc.contributor.author	Li, Yin-Ji
dc.contributor.author	Yoshida, Hiroki
dc.contributor.author	Miyamoto, Hiroshi
dc.contributor.author	Gay, Steffen
dc.contributor.author	Pessler, Frank
dc.contributor.author	Shobuike, Takeo
dc.date.accessioned	2012-03-07T10:39:20Z
dc.date.available	2012-03-07T10:39:20Z
dc.date.issued	2011-09
dc.identifier.citation	The transcription factor FBI-1/OCZF/LRF is expressed in osteoclasts and regulates RANKL-induced osteoclast formation in vitro and in vivo. 2011, 63 (9):2744-54 Arthritis Rheum.	en
dc.identifier.issn	1529-0131
dc.identifier.pmid	21590684
dc.identifier.doi	10.1002/art.30455
dc.identifier.uri	http://hdl.handle.net/10033/214592
dc.description.abstract	Since transcription factors expressed in osteoclasts are possible targets for regulation of bone destruction in bone disorders, we investigated the expression of the transcription factor FBI-1/OCZF/LRF (in humans, factor that binds to inducer of short transcripts of human immunodeficiency virus type 1; in rats, osteoclast-derived zinc finger; in mice, leukemia/lymphoma-related factor) in patients with rheumatoid arthritis (RA), and assessed its role in osteoclastogenesis in vivo.
dc.language.iso	en	en
dc.subject.mesh	Animals	en
dc.subject.mesh	Arthritis, Experimental	en
dc.subject.mesh	Arthritis, Rheumatoid	en
dc.subject.mesh	Bone Density	en
dc.subject.mesh	Bone and Bones	en
dc.subject.mesh	Cell Differentiation	en
dc.subject.mesh	DNA-Binding Proteins	en
dc.subject.mesh	Female	en
dc.subject.mesh	Humans	en
dc.subject.mesh	Macrophages	en
dc.subject.mesh	Male	en
dc.subject.mesh	Mice	en
dc.subject.mesh	Mice, Transgenic	en
dc.subject.mesh	Osteoblasts	en
dc.subject.mesh	Osteoclasts	en
dc.subject.mesh	RANK Ligand	en
dc.subject.mesh	Rats	en
dc.subject.mesh	Transcription Factors	en
dc.title	The transcription factor FBI-1/OCZF/LRF is expressed in osteoclasts and regulates RANKL-induced osteoclast formation in vitro and in vivo.	en
dc.type	Article	en
dc.contributor.department	Department of Microbiology, Faculty of Medicine, Saga University, Saga, Japan. kukita@cc.saga-u.ac.jp	en
dc.identifier.journal	Arthritis and rheumatism	en
refterms.dateFOA	2012-09-15T00:00:00Z
html.description.abstract	Since transcription factors expressed in osteoclasts are possible targets for regulation of bone destruction in bone disorders, we investigated the expression of the transcription factor FBI-1/OCZF/LRF (in humans, factor that binds to inducer of short transcripts of human immunodeficiency virus type 1; in rats, osteoclast-derived zinc finger; in mice, leukemia/lymphoma-related factor) in patients with rheumatoid arthritis (RA), and assessed its role in osteoclastogenesis in vivo.