Gene expression profiles of T cells from hepatitis E virus infected patients in acute and resolving phase.
dc.contributor.author | TrehanPati, Nirupma | |
dc.contributor.author | Sukriti, Sukriti | |
dc.contributor.author | Geffers, Robert | |
dc.contributor.author | Hissar, Syed | |
dc.contributor.author | Riese, Peggy | |
dc.contributor.author | Toepfer, Tanja | |
dc.contributor.author | Guzman, Carlos A | |
dc.contributor.author | Sarin, Shiv Kumar | |
dc.date.accessioned | 2012-03-28T13:19:57Z | en |
dc.date.available | 2012-03-28T13:19:57Z | en |
dc.date.issued | 2011-06 | en |
dc.identifier.citation | Gene expression profiles of T cells from hepatitis E virus infected patients in acute and resolving phase. 2011, 31 (3):498-508 J. Clin. Immunol. | en_GB |
dc.identifier.issn | 1573-2592 | en |
dc.identifier.pmid | 21287396 | en |
dc.identifier.doi | 10.1007/s10875-010-9506-2 | en |
dc.identifier.uri | http://hdl.handle.net/10033/216864 | en |
dc.description.abstract | Approximately 50% of acute viral hepatitis in young adults and in pregnant women is due to hepatitis E virus (HEV) infection in developing countries. T cell-mediated immune injury probably plays a key role in the pathogenesis of acute hepatitis illness. However, there is a paucity of data on the global gene expression programs activated on T cells, which are subsequently responsible for T cell recruitment to the liver and triggering of immune injury. | |
dc.language.iso | en | en |
dc.rights | Archived with thanks to Journal of clinical immunology | en_GB |
dc.subject.mesh | Acute Disease | en_GB |
dc.subject.mesh | Adult | en_GB |
dc.subject.mesh | Antigens, CD11a | en_GB |
dc.subject.mesh | Antigens, CD45 | en_GB |
dc.subject.mesh | Biological Markers | en_GB |
dc.subject.mesh | Case-Control Studies | en_GB |
dc.subject.mesh | Convalescence | en_GB |
dc.subject.mesh | Disease Progression | en_GB |
dc.subject.mesh | Female | en_GB |
dc.subject.mesh | Flow Cytometry | en_GB |
dc.subject.mesh | Gene Expression Profiling | en_GB |
dc.subject.mesh | Hepatitis E | en_GB |
dc.subject.mesh | Hepatitis E virus | en_GB |
dc.subject.mesh | Humans | en_GB |
dc.subject.mesh | Liver | en_GB |
dc.subject.mesh | Male | en_GB |
dc.subject.mesh | Oligonucleotide Array Sequence Analysis | en_GB |
dc.subject.mesh | Receptors, CCR5 | en_GB |
dc.subject.mesh | Reverse Transcriptase Polymerase Chain Reaction | en_GB |
dc.subject.mesh | T-Lymphocytes | en_GB |
dc.subject.mesh | Young Adult | en_GB |
dc.title | Gene expression profiles of T cells from hepatitis E virus infected patients in acute and resolving phase. | en |
dc.type | Article | en |
dc.contributor.department | Institute of Liver and Biliary Sciences, D-1, Vasant Kunj, 110 070, New Delhi, India. trehanpati@gmail.com | en_GB |
dc.identifier.journal | Journal of clinical immunology | en_GB |
refterms.dateFOA | 2018-06-12T23:49:21Z | |
html.description.abstract | Approximately 50% of acute viral hepatitis in young adults and in pregnant women is due to hepatitis E virus (HEV) infection in developing countries. T cell-mediated immune injury probably plays a key role in the pathogenesis of acute hepatitis illness. However, there is a paucity of data on the global gene expression programs activated on T cells, which are subsequently responsible for T cell recruitment to the liver and triggering of immune injury. |