Immunization with live virus vaccine protects highly susceptible DBA/2J mice from lethal influenza A H1N1 infection.
dc.contributor.author | Dengler, Leonie | |
dc.contributor.author | May, Mathias | |
dc.contributor.author | Wilk, Esther | |
dc.contributor.author | Bahgat, Mahmoud M | |
dc.contributor.author | Schughart, Klaus | |
dc.date.accessioned | 2013-05-07T08:54:54Z | en |
dc.date.available | 2013-05-07T08:54:54Z | en |
dc.date.issued | 2012 | en |
dc.identifier.citation | Immunization with live virus vaccine protects highly susceptible DBA/2J mice from lethal influenza A H1N1 infection. 2012, 9:212 Virol. J. | en_GB |
dc.identifier.issn | 1743-422X | en |
dc.identifier.pmid | 22992381 | en |
dc.identifier.doi | 10.1186/1743-422X-9-212 | en |
dc.identifier.uri | http://hdl.handle.net/10033/288579 | en |
dc.description.abstract | The mouse represents an important model system to study the host response to influenza A infections and to evaluate new prevention or treatment strategies. We and others reported that the susceptibility to influenza A virus infections strongly varies among different inbred mouse strains. In particular, DBA/2J mice are highly susceptible to several influenza A subtypes, including human isolates and exhibit severe symptoms after infection with clinical isolates. | |
dc.language.iso | en | en |
dc.rights | Archived with thanks to Virology journal | en_GB |
dc.subject.mesh | Animals | en_GB |
dc.subject.mesh | Antibodies, Viral | en_GB |
dc.subject.mesh | Antibody Specificity | en_GB |
dc.subject.mesh | Disease Models, Animal | en_GB |
dc.subject.mesh | Humans | en_GB |
dc.subject.mesh | Immunoglobulin G | en_GB |
dc.subject.mesh | Influenza A Virus, H1N1 Subtype | en_GB |
dc.subject.mesh | Influenza Vaccines | en_GB |
dc.subject.mesh | Mice | en_GB |
dc.subject.mesh | Mice, Inbred C57BL | en_GB |
dc.subject.mesh | Mice, Inbred DBA | en_GB |
dc.subject.mesh | Orthomyxoviridae Infections | en_GB |
dc.subject.mesh | Vaccines, Attenuated | en_GB |
dc.title | Immunization with live virus vaccine protects highly susceptible DBA/2J mice from lethal influenza A H1N1 infection. | en |
dc.type | Article | en |
dc.contributor.department | Department of Infection Genetics, Helmholtz Centre for Infection Research and University of Veterinary Medicine Hannover, Inhoffenstr. 7, D-38124 Braunschweig, Germany. | en_GB |
dc.identifier.journal | Virology journal | en_GB |
refterms.dateFOA | 2018-06-12T21:36:13Z | |
html.description.abstract | The mouse represents an important model system to study the host response to influenza A infections and to evaluate new prevention or treatment strategies. We and others reported that the susceptibility to influenza A virus infections strongly varies among different inbred mouse strains. In particular, DBA/2J mice are highly susceptible to several influenza A subtypes, including human isolates and exhibit severe symptoms after infection with clinical isolates. |