Name:
Nitsche-Schmitz and Chhatwal_f ...
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original manuscript
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Issue Date
2013
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Show full item recordAbstract
Otherwise uncomplicated infections with Streptococcus pyogenes can cause two insidious immune sequelae known as post-streptococcal glomerulonephritis (PSGN) and acute rheumatic fever (ARF). These diseases follow with a latency of a few weeks or months after primary infection and are responsible for high mortality and morbidity. PSGN has also been linked to infections with group C streptococci of the species S. equi ssp. zooepidemicus (SESZ). Moreover, there are some indications that infection with group C and G streptococci (GCGS) of the subspecies Streptococcus dysgalactiae ssp. equisimilis (SDSE) leads to ARF. Despite decades of research, the picture of the molecular pathogenesis of streptococcal immune sequelae resembles a jigsaw puzzle. Herein we try to put some of the puzzle bits together that have been collected till date.Citation
Host-pathogen interactions in streptococcal immune sequelae. 2013, 368:155-71 Curr. Top. Microbiol. Immunol.Affiliation
Helmholtz Centre for Infection Research, Inhoffenstraße 7, D-38124 Braunschweig, Germany. Patric.Nitsche@helmholtz-hzi.dePubMed ID
23212184Type
Book chapterLanguage
enISSN
0070-217Xae974a485f413a2113503eed53cd6c53
10.1007/82_2012_296
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