Entry and replication of recombinant hepatitis C viruses in cell culture.

Vieyres, Gabrielle; Pietschmann, Thomas

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Authors

Vieyres, Gabrielle
Pietschmann, Thomas

Issue Date

2013-02

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Abstract

Hepatitis C virus (HCV) is a positive-strand enveloped RNA virus and belongs to the Flaviviridae family. The heavy health burden associated with the virus infection in humans and the intriguing peculiarities of the interaction between the HCV replication cycle and the hepatocyte host cell have stimulated a flourishing research field. The present review aims at recapitulating the different viral and cellular systems modelling HCV entry and replication, and in particular at gathering the tools available to dissect the HCV entry pathway.

Citation

Entry and replication of recombinant hepatitis C viruses in cell culture. 2013, 59 (2):233-48 Methods

Affiliation

Institute of Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research; A Joint Venture Between The Medical School Hannover and The Helmholtz Centre for Infection Research, Feodor-Lynen-Straße 7-9, 30625 Hannover, Germany.

Type

Article

Language

ISSN

1095-9130

Collections

publications of the work group experimental Virology([TC]EVIR)

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