Entry and replication of recombinant hepatitis C viruses in cell culture.

Vieyres, Gabrielle; Pietschmann, Thomas

dc.contributor.author	Vieyres, Gabrielle
dc.contributor.author	Pietschmann, Thomas
dc.date.accessioned	2013-08-19T12:21:26Z
dc.date.available	2013-08-19T12:21:26Z
dc.date.issued	2013-02
dc.identifier.citation	Entry and replication of recombinant hepatitis C viruses in cell culture. 2013, 59 (2):233-48 Methods	en_GB
dc.identifier.issn	1095-9130
dc.identifier.pmid	23009812
dc.identifier.doi	10.1016/j.ymeth.2012.09.005
dc.identifier.uri	http://hdl.handle.net/10033/299086
dc.description.abstract	Hepatitis C virus (HCV) is a positive-strand enveloped RNA virus and belongs to the Flaviviridae family. The heavy health burden associated with the virus infection in humans and the intriguing peculiarities of the interaction between the HCV replication cycle and the hepatocyte host cell have stimulated a flourishing research field. The present review aims at recapitulating the different viral and cellular systems modelling HCV entry and replication, and in particular at gathering the tools available to dissect the HCV entry pathway.
dc.language.iso	en	en
dc.rights	Archived with thanks to Methods (San Diego, Calif.)	en_GB
dc.title	Entry and replication of recombinant hepatitis C viruses in cell culture.	en
dc.type	Article	en
dc.contributor.department	Institute of Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research; A Joint Venture Between The Medical School Hannover and The Helmholtz Centre for Infection Research, Feodor-Lynen-Straße 7-9, 30625 Hannover, Germany.	en_GB
dc.identifier.journal	Methods (San Diego, Calif.)	en_GB
refterms.dateFOA	2018-06-12T23:06:36Z
html.description.abstract	Hepatitis C virus (HCV) is a positive-strand enveloped RNA virus and belongs to the Flaviviridae family. The heavy health burden associated with the virus infection in humans and the intriguing peculiarities of the interaction between the HCV replication cycle and the hepatocyte host cell have stimulated a flourishing research field. The present review aims at recapitulating the different viral and cellular systems modelling HCV entry and replication, and in particular at gathering the tools available to dissect the HCV entry pathway.