Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Chernikova, Tatyana N
Heipieper, Hermann J
Kotsyurbenko, Oleg R
Nechitaylo, Taras Y
Alain Petit, Pierre
Albar, Juan P
Reva, Oleg N
Yakunin, Alexander F
Yakimov, Michail M
Golyshina, Olga V
Golyshin, Peter N
MetadataShow full item record
AbstractUbiquitous bacteria from the genus Oleispira drive oil degradation in the largest environment on Earth, the cold and deep sea. Here we report the genome sequence of Oleispira antarctica and show that compared with Alcanivorax borkumensis-the paradigm of mesophilic hydrocarbonoclastic bacteria-O. antarctica has a larger genome that has witnessed massive gene-transfer events. We identify an array of alkane monooxygenases, osmoprotectants, siderophores and micronutrient-scavenging pathways. We also show that at low temperatures, the main protein-folding machine Cpn60 functions as a single heptameric barrel that uses larger proteins as substrates compared with the classical double-barrel structure observed at higher temperatures. With 11 protein crystal structures, we further report the largest set of structures from one psychrotolerant organism. The most common structural feature is an increased content of surface-exposed negatively charged residues compared to their mesophilic counterparts. Our findings are relevant in the context of microbial cold-adaptation mechanisms and the development of strategies for oil-spill mitigation in cold environments.
CitationGenome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica. 2013, 4:2156 Nat Commun
Affiliation1] Max-Planck Institute for Molecular Genetics, Berlin-Dahlem D-14195, Germany  Section Phytomedicine, Department of Crop and Animal Sciences, Humboldt-Universität zu Berlin, Berlin-Dahlem D-14195, Germany.
The following license files are associated with this item:
- Genome sequence of the alkane-degrading bacterium Alcanivorax hongdengensis type strain A-11-3.
- Authors: Lai Q, Shao Z
- Issue date: 2012 Dec
- The genome analysis of Oleiphilus messinensis ME102 (DSM 13489<sup>T</sup>) reveals backgrounds of its obligate alkane-devouring marine lifestyle.
- Authors: Toshchakov SV, Korzhenkov AA, Chernikova TN, Ferrer M, Golyshina OV, Yakimov MM, Golyshin PN
- Issue date: 2017 Dec
- Shewanella spp. genomic evolution for a cold marine lifestyle and in-situ explosive biodegradation.
- Authors: Zhao JS, Deng Y, Manno D, Hawari J
- Issue date: 2010 Feb 8
- Transcriptional profiling of the marine oil-degrading bacterium Alcanivorax borkumensis during growth on n-alkanes.
- Authors: Sabirova JS, Becker A, Lünsdorf H, Nicaud JM, Timmis KN, Golyshin PN
- Issue date: 2011 Jun
- Gene diversity of CYP153A and AlkB alkane hydroxylases in oil-degrading bacteria isolated from the Atlantic Ocean.
- Authors: Wang L, Wang W, Lai Q, Shao Z
- Issue date: 2010 May