The relative composition of the inflammatory infiltrate as an additional tool for synovial tissue classification.
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Authors
Della Beffa, CristinaSlansky, Elisabeth
Pommerenke, Claudia

Klawonn, Frank

Li, Jialiang
Dai, Lie
Schumacher, H Ralph
Pessler, Frank
Issue Date
2013
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Show full item recordAbstract
Traditionally, differences in absolute numbers of cells expressing a certain marker (e.g., positive staining cells per mm(2)) have been used in immunohistological synovial tissue classification. We have begun to evaluate the relative composition of the inflammatory infiltrates, i.e. percentages of inflammatory cell types in inflammatory infiltrates, as an alternate classification tool that may potentially improve tissue diagnostics, subgrouping in clinical trials, and understanding of pathogenesis of inflammatory and noninflammatory arthropathies.Citation
The relative composition of the inflammatory infiltrate as an additional tool for synovial tissue classification. 2013, 8 (8):e72494 PLoS ONEAffiliation
Department of Cellular Proteomics, Helmholtz Centre for Infection Research, Braunschweig, Germany.Journal
PloS onePubMed ID
23951325Type
ArticleLanguage
enISSN
1932-6203ae974a485f413a2113503eed53cd6c53
10.1371/journal.pone.0072494
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