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dc.contributor.authorBalabanova, Yanina
dc.contributor.authorKlar, Stefanie
dc.contributor.authorDeleré, Yvonne
dc.contributor.authorWilking, Hendrik
dc.contributor.authorFaber, Mirko S
dc.contributor.authorLassen, Sofie Gillesberg
dc.contributor.authorGilsdorf, Andreas
dc.contributor.authorDupke, Susann
dc.contributor.authorNitschke, Martin
dc.contributor.authorSayk, Friedhelm
dc.contributor.authorGrunow, Roland
dc.contributor.authorKrause, Gerard
dc.date.accessioned2013-09-24T13:28:54Zen
dc.date.available2013-09-24T13:28:54Zen
dc.date.issued2013en
dc.identifier.citationSerological Evidence of Asymptomatic Infections during Escherichia coli O104:H4 Outbreak in Germany in 2011. 2013, 8 (9):e73052 PLoS ONEen
dc.identifier.issn1932-6203en
dc.identifier.pmid24039858en
dc.identifier.doi10.1371/journal.pone.0073052en
dc.identifier.urihttp://hdl.handle.net/10033/302198en
dc.description.abstractThe largest known outbreak caused by a rare hybrid strain of Shiga toxin-producing E.coli (STEC) and enteroaggregative E. coli (EAEC) (E.coli O104:H4) of serotype O104:H4 occurred in Germany in 2011. Fenugreek sprouts acted as a transmission vehicle and were widely consumed in the outbreak area at the time of the epidemic. In total 3,842 people developed a clinical illness caused by this strain; however the rates of asymptomatic infections remain unclear. We aimed to develop a serological assay for detection of E.coli O104 LPS specific antibodies and to establish the post-outbreak levels of seropositivity among people with documented exposure to contaminated sprouts.
dc.language.isoenen
dc.rightsArchived with thanks to PloS oneen
dc.titleSerological Evidence of Asymptomatic Infections during Escherichia coli O104:H4 Outbreak in Germany in 2011.en
dc.typeArticleen
dc.contributor.departmentRobert Koch Institute, Berlin, Germany.en
dc.identifier.journalPloS oneen
refterms.dateFOA2018-06-12T23:04:23Z
html.description.abstractThe largest known outbreak caused by a rare hybrid strain of Shiga toxin-producing E.coli (STEC) and enteroaggregative E. coli (EAEC) (E.coli O104:H4) of serotype O104:H4 occurred in Germany in 2011. Fenugreek sprouts acted as a transmission vehicle and were widely consumed in the outbreak area at the time of the epidemic. In total 3,842 people developed a clinical illness caused by this strain; however the rates of asymptomatic infections remain unclear. We aimed to develop a serological assay for detection of E.coli O104 LPS specific antibodies and to establish the post-outbreak levels of seropositivity among people with documented exposure to contaminated sprouts.


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