ATR-FTIR spectroscopy reveals genomic loci regulating the tissue response in high fat diet fed BXD recombinant inbred mouse strains.
| dc.contributor.author | Lasch, Peter | |
| dc.contributor.author | Neuschl, Christina | |
| dc.contributor.author | Millrose, Marion K | |
| dc.contributor.author | Alberts, Rudi | |
| dc.contributor.author | Schughart, Klaus | |
| dc.contributor.author | Naumann, Dieter | |
| dc.contributor.author | Brockmann, Gudrun A | |
| dc.date.accessioned | 2013-11-12T15:31:52Z | en |
| dc.date.available | 2013-11-12T15:31:52Z | en |
| dc.date.issued | 2013 | en |
| dc.identifier.citation | ATR-FTIR spectroscopy reveals genomic loci regulating the tissue response in high fat diet fed BXD recombinant inbred mouse strains. 2013, 14:386 BMC Genomics | en |
| dc.identifier.issn | 1471-2164 | en |
| dc.identifier.pmid | 23758785 | en |
| dc.identifier.doi | 10.1186/1471-2164-14-386 | en |
| dc.identifier.uri | http://hdl.handle.net/10033/305259 | en |
| dc.description.abstract | Obesity-associated organ-specific pathological states can be ensued from the dysregulation of the functions of the adipose tissues, liver and muscle. However, the influence of genetic differences underlying gross-compositional differences in these tissues is largely unknown. In the present study, the analytical method of ATR-FTIR spectroscopy has been combined with a genetic approach to identify genetic differences responsible for phenotypic alterations in adipose, liver and muscle tissues. | |
| dc.language.iso | en | en |
| dc.rights | Archived with thanks to BMC genomics | en |
| dc.subject.mesh | Animals | en |
| dc.subject.mesh | DNA, Recombinant | en |
| dc.subject.mesh | Diet, High-Fat | en |
| dc.subject.mesh | Genomics | en |
| dc.subject.mesh | Inbreeding | en |
| dc.subject.mesh | Male | en |
| dc.subject.mesh | Mice | en |
| dc.subject.mesh | Phenotype | en |
| dc.subject.mesh | Quantitative Trait Loci | en |
| dc.subject.mesh | Spectroscopy, Fourier Transform Infrared | en |
| dc.title | ATR-FTIR spectroscopy reveals genomic loci regulating the tissue response in high fat diet fed BXD recombinant inbred mouse strains. | en |
| dc.type | Article | en |
| dc.contributor.department | Department for Crop and Animal Sciences, Humboldt-Universität zu Berlin, Invalidenstraße 42, 10115, Berlin, Germany. | en |
| dc.identifier.journal | BMC genomics | en |
| refterms.dateFOA | 2018-06-13T14:06:52Z | |
| html.description.abstract | Obesity-associated organ-specific pathological states can be ensued from the dysregulation of the functions of the adipose tissues, liver and muscle. However, the influence of genetic differences underlying gross-compositional differences in these tissues is largely unknown. In the present study, the analytical method of ATR-FTIR spectroscopy has been combined with a genetic approach to identify genetic differences responsible for phenotypic alterations in adipose, liver and muscle tissues. |
