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dc.contributor.authorKaput, Jim
dc.contributor.authorCotton, Richard G H
dc.contributor.authorHardman, Lauren
dc.contributor.authorWatson, Michael
dc.contributor.authorAl Aqeel, Aida I
dc.contributor.authorAl-Aama, Jumana Y
dc.contributor.authorAl-Mulla, Fahd
dc.contributor.authorAlonso, Santos
dc.contributor.authorAretz, Stefan
dc.contributor.authorAuerbach, Arleen D
dc.contributor.authorBapat, Bharati
dc.contributor.authorBernstein, Inge T
dc.contributor.authorBhak, Jong
dc.contributor.authorBleoo, Stacey L
dc.contributor.authorBlöcker, Helmut
dc.contributor.authorBrenner, Steven E
dc.contributor.authorBurn, John
dc.contributor.authorBustamante, Mariona
dc.contributor.authorCalzone, Rita
dc.contributor.authorCambon-Thomsen, Anne
dc.contributor.authorCargill, Michele
dc.contributor.authorCarrera, Paola
dc.contributor.authorCavedon, Lawrence
dc.contributor.authorCho, Yoon Shin
dc.contributor.authorChung, Yeun-Jun
dc.contributor.authorClaustres, Mireille
dc.contributor.authorCutting, Garry
dc.contributor.authorDalgleish, Raymond
dc.contributor.authorden Dunnen, Johan T
dc.contributor.authorDíaz, Carlos
dc.contributor.authorDobrowolski, Steven
dc.contributor.authordos Santos, M Rosário N
dc.contributor.authorEkong, Rosemary
dc.contributor.authorFlanagan, Simon B
dc.contributor.authorFlicek, Paul
dc.contributor.authorFurukawa, Yoichi
dc.contributor.authorGenuardi, Maurizio
dc.contributor.authorGhang, Ho
dc.contributor.authorGolubenko, Maria V
dc.contributor.authorGreenblatt, Marc S
dc.contributor.authorHamosh, Ada
dc.contributor.authorHancock, John M
dc.contributor.authorHardison, Ross
dc.contributor.authorHarrison, Terence M
dc.contributor.authorHoffmann, Robert
dc.contributor.authorHoraitis, Rania
dc.contributor.authorHoward, Heather J
dc.contributor.authorBarash, Carol Isaacson
dc.contributor.authorIzagirre, Neskuts
dc.contributor.authorJung, Jongsun
dc.contributor.authorKojima, Toshio
dc.contributor.authorLaradi, Sandrine
dc.contributor.authorLee, Yeon-Su
dc.contributor.authorLee, Jong-Young
dc.contributor.authorGil-da-Silva-Lopes, Vera L
dc.contributor.authorMacrae, Finlay A
dc.contributor.authorMaglott, Donna
dc.contributor.authorMarafie, Makia J
dc.contributor.authorMarsh, Steven G E
dc.contributor.authorMatsubara, Yoichi
dc.contributor.authorMessiaen, Ludwine M
dc.contributor.authorMöslein, Gabriela
dc.contributor.authorNetea, Mihai G
dc.contributor.authorNorton, Melissa L
dc.contributor.authorOefner, Peter J
dc.contributor.authorOetting, William S
dc.contributor.authorO'Leary, James C
dc.contributor.authorde Ramirez, Ana Maria Oller
dc.contributor.authorPaalman, Mark H
dc.contributor.authorParboosingh, Jillian
dc.contributor.authorPatrinos, George P
dc.contributor.authorPerozzi, Giuditta
dc.contributor.authorPhillips, Ian R
dc.contributor.authorPovey, Sue
dc.contributor.authorPrasad, Suyash
dc.contributor.authorQi, Ming
dc.contributor.authorQuin, David J
dc.contributor.authorRamesar, Rajkumar S
dc.contributor.authorRichards, C Sue
dc.contributor.authorSavige, Judith
dc.contributor.authorScheible, Dagmar G
dc.contributor.authorScott, Rodney J
dc.contributor.authorSeminara, Daniela
dc.contributor.authorShephard, Elizabeth A
dc.contributor.authorSijmons, Rolf H
dc.contributor.authorSmith, Timothy D
dc.contributor.authorSobrido, María-Jesús
dc.contributor.authorTanaka, Toshihiro
dc.contributor.authorTavtigian, Sean V
dc.contributor.authorTaylor, Graham R
dc.contributor.authorTeague, Jon
dc.contributor.authorTöpel, Thoralf
dc.contributor.authorUllman-Cullere, Mollie
dc.contributor.authorUtsunomiya, Joji
dc.contributor.authorvan Kranen, Henk J
dc.contributor.authorVihinen, Mauno
dc.contributor.authorWebb, Elizabeth
dc.contributor.authorWeber, Thomas K
dc.contributor.authorYeager, Meredith
dc.contributor.authorYeom, Young I
dc.contributor.authorYim, Seon-Hee
dc.contributor.authorYoo, Hyang-Sook
dc.date.accessioned2013-12-04T13:55:25Z
dc.date.available2013-12-04T13:55:25Z
dc.date.issued2009-04
dc.identifier.citationPlanning the human variome project: the Spain report. 2009, 30 (4):496-510 Hum. Mutat.en
dc.identifier.issn1098-1004
dc.identifier.pmid19306394
dc.identifier.doi10.1002/humu.20972
dc.identifier.urihttp://hdl.handle.net/10033/306271
dc.description.abstractThe remarkable progress in characterizing the human genome sequence, exemplified by the Human Genome Project and the HapMap Consortium, has led to the perception that knowledge and the tools (e.g., microarrays) are sufficient for many if not most biomedical research efforts. A large amount of data from diverse studies proves this perception inaccurate at best, and at worst, an impediment for further efforts to characterize the variation in the human genome. Because variation in genotype and environment are the fundamental basis to understand phenotypic variability and heritability at the population level, identifying the range of human genetic variation is crucial to the development of personalized nutrition and medicine. The Human Variome Project (HVP; http://www.humanvariomeproject.org/) was proposed initially to systematically collect mutations that cause human disease and create a cyber infrastructure to link locus specific databases (LSDB). We report here the discussions and recommendations from the 2008 HVP planning meeting held in San Feliu de Guixols, Spain, in May 2008.
dc.language.isoenen
dc.rightsArchived with thanks to Human mutationen
dc.subject.meshComputational Biologyen
dc.subject.meshDatabases, Geneticen
dc.subject.meshGenetic Predisposition to Diseaseen
dc.subject.meshGenetic Variationen
dc.subject.meshGenome, Humanen
dc.subject.meshGenotypeen
dc.subject.meshHumansen
dc.subject.meshInformation Disseminationen
dc.subject.meshMutationen
dc.subject.meshPhenotypeen
dc.subject.meshPolymorphism, Geneticen
dc.subject.meshSpainen
dc.titlePlanning the human variome project: the Spain report.en
dc.typeArticleen
dc.contributor.departmentDivision of Personalised Nutrition and Medicine, FDA/National Center for Toxicological Research, Jefferson, Arkansas 72079, USA. James.kaput@fda.hhs.goven
dc.identifier.journalHuman mutationen
refterms.dateFOA2018-06-13T17:10:40Z
html.description.abstractThe remarkable progress in characterizing the human genome sequence, exemplified by the Human Genome Project and the HapMap Consortium, has led to the perception that knowledge and the tools (e.g., microarrays) are sufficient for many if not most biomedical research efforts. A large amount of data from diverse studies proves this perception inaccurate at best, and at worst, an impediment for further efforts to characterize the variation in the human genome. Because variation in genotype and environment are the fundamental basis to understand phenotypic variability and heritability at the population level, identifying the range of human genetic variation is crucial to the development of personalized nutrition and medicine. The Human Variome Project (HVP; http://www.humanvariomeproject.org/) was proposed initially to systematically collect mutations that cause human disease and create a cyber infrastructure to link locus specific databases (LSDB). We report here the discussions and recommendations from the 2008 HVP planning meeting held in San Feliu de Guixols, Spain, in May 2008.


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