A study of Chitosan and c-di-GMP as mucosal adjuvants for intranasal influenza H5N1 vaccine.

Svindland, Signe C; Pedersen, Gabriel K; Pathirana, Rishi D; Bredholt, Geir; Nøstbakken, Jane K; Jul-Larsen, Åsne; Guzmán, Carlos A; Montomoli, Emanuele; Lapini, Giulia; Piccirella, Simona; Jabbal-Gill, Inderjit; Hinchcliffe, Michael; Cox, Rebecca J

dc.contributor.author	Svindland, Signe C
dc.contributor.author	Pedersen, Gabriel K
dc.contributor.author	Pathirana, Rishi D
dc.contributor.author	Bredholt, Geir
dc.contributor.author	Nøstbakken, Jane K
dc.contributor.author	Jul-Larsen, Åsne
dc.contributor.author	Guzmán, Carlos A
dc.contributor.author	Montomoli, Emanuele
dc.contributor.author	Lapini, Giulia
dc.contributor.author	Piccirella, Simona
dc.contributor.author	Jabbal-Gill, Inderjit
dc.contributor.author	Hinchcliffe, Michael
dc.contributor.author	Cox, Rebecca J
dc.date.accessioned	2014-01-14T15:11:57Z
dc.date.available	2014-01-14T15:11:57Z
dc.date.issued	2013-11
dc.identifier.citation	A study of Chitosan and c-di-GMP as mucosal adjuvants for intranasal influenza H5N1 vaccine. 2013, 7 (6):1181-93 Influenza Other Respir Viruses	en
dc.identifier.issn	1750-2659
dc.identifier.pmid	23170900
dc.identifier.doi	10.1111/irv.12056
dc.identifier.uri	http://hdl.handle.net/10033/311297
dc.description.abstract	Highly pathogenic avian influenza A/H5N1 virus remains a potential pandemic threat, and it is essential to continue vaccine development against this subtype. A local mucosal immune response in the upper respiratory tract may stop influenza transmission. It is therefore important to develop effective intranasal pandemic influenza vaccines that induce mucosal immunity at the site of viral entry.
dc.language.iso	en	en
dc.rights	Archived with thanks to Influenza and other respiratory viruses	en
dc.title	A study of Chitosan and c-di-GMP as mucosal adjuvants for intranasal influenza H5N1 vaccine.	en
dc.type	Article	en
dc.contributor.department	department of vaccinology and applied microbiology, Helmholtz Centre for infection research, D38124 Braunschweig, Germany	en
dc.identifier.journal	Influenza and other respiratory viruses	en
refterms.dateFOA	2018-06-12T22:45:20Z
html.description.abstract	Highly pathogenic avian influenza A/H5N1 virus remains a potential pandemic threat, and it is essential to continue vaccine development against this subtype. A local mucosal immune response in the upper respiratory tract may stop influenza transmission. It is therefore important to develop effective intranasal pandemic influenza vaccines that induce mucosal immunity at the site of viral entry.