Investigating the Association of ApoE Genotypes with Blood-Brain Barrier Dysfunction Measured by Cerebrospinal Fluid-Serum Albumin Ratio in a Cohort of Patients with Different Types of Dementia.
dc.contributor.author | Karch, André | |
dc.contributor.author | Manthey, Henrike | |
dc.contributor.author | Ponto, Claudia | |
dc.contributor.author | Hermann, Peter | |
dc.contributor.author | Heinemann, Uta | |
dc.contributor.author | Schmidt, Christian | |
dc.contributor.author | Zerr, Inga | |
dc.date.accessioned | 2014-01-21T13:24:20Z | |
dc.date.available | 2014-01-21T13:24:20Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Investigating the Association of ApoE Genotypes with Blood-Brain Barrier Dysfunction Measured by Cerebrospinal Fluid-Serum Albumin Ratio in a Cohort of Patients with Different Types of Dementia. 2013, 8 (12):e84405 PLoS ONE | en |
dc.identifier.issn | 1932-6203 | |
dc.identifier.pmid | 24386372 | |
dc.identifier.doi | 10.1371/journal.pone.0084405 | |
dc.identifier.uri | http://hdl.handle.net/10033/311617 | |
dc.description.abstract | Since more than a decade ApoE is known to be a strong risk factor for Alzheimer's disease (AD); however, molecular pathways mediating this risk are still unclear. In recent years it has been hypothesized that ApoE might play a role in the disintegration of blood-brain barrier (BBB). In the present study we addressed the question if ApoE genotypes might be associated with BBB function measured by albumin ratio (QAlb) in a large cohort of patients with different types of dementia. | |
dc.language.iso | en | en |
dc.rights | Archived with thanks to PloS one | en |
dc.title | Investigating the Association of ApoE Genotypes with Blood-Brain Barrier Dysfunction Measured by Cerebrospinal Fluid-Serum Albumin Ratio in a Cohort of Patients with Different Types of Dementia. | en |
dc.type | Article | en |
dc.identifier.journal | PloS one | en |
refterms.dateFOA | 2018-06-12T18:12:24Z | |
html.description.abstract | Since more than a decade ApoE is known to be a strong risk factor for Alzheimer's disease (AD); however, molecular pathways mediating this risk are still unclear. In recent years it has been hypothesized that ApoE might play a role in the disintegration of blood-brain barrier (BBB). In the present study we addressed the question if ApoE genotypes might be associated with BBB function measured by albumin ratio (QAlb) in a large cohort of patients with different types of dementia. |