New approaches to control infections: anti-biofilm strategies against gram-negative bacteria.
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Issue Date
2013
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Show full item recordAbstract
Hospital-acquired bacterial infections, especially with Gram-negative pathogens, present a major threat due to the rapid spread of antibiotic-resistant strains. Targeting mechanisms of bacterial virulence has recently appeared as a promising new therapeutic paradigm. Biofilm formation is a bacterial lifestyle, which offers a survival advantage through its protective matrix against host immune defense and antibiotic treatment. Interfering with biogenesis of adhesive organelles, bacterial communication or carbohydrate-mediated adhesion as anti-biofilm strategies are reviewed.Citation
New approaches to control infections: anti-biofilm strategies against gram-negative bacteria. 2013, 67 (4):286-90 Chimia (Aarau)Affiliation
University of Konstanz, Department of Chemistry and Zukunftskolleg, Universitätsstrasse 10, D-78457 Konstanz.Journal
ChimiaPubMed ID
23967708Type
ArticleLanguage
enISSN
0009-4293The following license files are associated with this item: