New approaches to control infections: anti-biofilm strategies against gram-negative bacteria.

Sommer, Roman; Joachim, Ines; Wagner, Stefanie; Titz, Alexander

dc.contributor.author	Sommer, Roman
dc.contributor.author	Joachim, Ines
dc.contributor.author	Wagner, Stefanie
dc.contributor.author	Titz, Alexander
dc.date.accessioned	2014-12-05T09:59:07Z
dc.date.available	2014-12-05T09:59:07Z
dc.date.issued	2013
dc.identifier.citation	New approaches to control infections: anti-biofilm strategies against gram-negative bacteria. 2013, 67 (4):286-90 Chimia (Aarau)	en
dc.identifier.issn	0009-4293
dc.identifier.pmid	23967708
dc.identifier.uri	http://hdl.handle.net/10033/336700
dc.description.abstract	Hospital-acquired bacterial infections, especially with Gram-negative pathogens, present a major threat due to the rapid spread of antibiotic-resistant strains. Targeting mechanisms of bacterial virulence has recently appeared as a promising new therapeutic paradigm. Biofilm formation is a bacterial lifestyle, which offers a survival advantage through its protective matrix against host immune defense and antibiotic treatment. Interfering with biogenesis of adhesive organelles, bacterial communication or carbohydrate-mediated adhesion as anti-biofilm strategies are reviewed.
dc.language.iso	en	en
dc.subject.mesh	Anti-Bacterial Agents	en
dc.subject.mesh	Biofilms	en
dc.subject.mesh	Cross Infection	en
dc.subject.mesh	Gram-Negative Bacteria	en
dc.subject.mesh	Gram-Negative Bacterial Infections	en
dc.subject.mesh	Humans	en
dc.title	New approaches to control infections: anti-biofilm strategies against gram-negative bacteria.	en
dc.type	Article	en
dc.contributor.department	University of Konstanz, Department of Chemistry and Zukunftskolleg, Universitätsstrasse 10, D-78457 Konstanz.	en
dc.identifier.journal	Chimia	en
refterms.dateFOA	2018-06-13T21:23:47Z
html.description.abstract	Hospital-acquired bacterial infections, especially with Gram-negative pathogens, present a major threat due to the rapid spread of antibiotic-resistant strains. Targeting mechanisms of bacterial virulence has recently appeared as a promising new therapeutic paradigm. Biofilm formation is a bacterial lifestyle, which offers a survival advantage through its protective matrix against host immune defense and antibiotic treatment. Interfering with biogenesis of adhesive organelles, bacterial communication or carbohydrate-mediated adhesion as anti-biofilm strategies are reviewed.