Investigation of cytochromes P450 in myxobacteria: excavation of cytochromes P450 from the genome of Sorangium cellulosum So ce56.

Khatri, Yogan; Hannemann, Frank; Perlova, Olena; Müller, Rolf; Bernhardt, Rita

dc.contributor.author	Khatri, Yogan
dc.contributor.author	Hannemann, Frank
dc.contributor.author	Perlova, Olena
dc.contributor.author	Müller, Rolf
dc.contributor.author	Bernhardt, Rita
dc.date.accessioned	2015-02-26T12:43:15Z	en
dc.date.available	2015-02-26T12:43:15Z	en
dc.date.issued	2011-06-06	en
dc.identifier.citation	Investigation of cytochromes P450 in myxobacteria: excavation of cytochromes P450 from the genome of Sorangium cellulosum So ce56. 2011, 585 (11):1506-13 FEBS Lett.	en
dc.identifier.issn	1873-3468	en
dc.identifier.pmid	21521637	en
dc.identifier.doi	10.1016/j.febslet.2011.04.035	en
dc.identifier.uri	http://hdl.handle.net/10033/345407	en
dc.description.abstract	The exploitation of cytochromes P450 for novel biotechnological application and for the investigation of their physiological function is of great scientific interest in this post genomic era, where an extraordinary biodiversity of P450 genes has been derived from all forms of life. The study of P450s in the myxobacterium Sorangium cellulosum strain So ce56, the producer of novel secondary metabolites of pharmaceutical interest is the research topic, in which we were engaged since the beginning of its genome sequencing project. We herein disclosed the cytochrome P450 complements (CYPomes) of spore-forming myxobacterial species, Stigmatella aurantiaca DW4/3-1, Haliangium ochraceum DSM 14365 and Myxococcus xanthus DK1622, and their potential pharmaceutical significance has been discussed.
dc.language.iso	en	en
dc.subject.mesh	Cytochrome P-450 Enzyme System	en
dc.subject.mesh	Genome, Bacterial	en
dc.subject.mesh	Genomics	en
dc.subject.mesh	Myxococcales	en
dc.subject.mesh	Spores, Bacterial	en
dc.title	Investigation of cytochromes P450 in myxobacteria: excavation of cytochromes P450 from the genome of Sorangium cellulosum So ce56.	en
dc.type	Article	en
dc.identifier.journal	FEBS letters	en
refterms.dateFOA	2018-06-13T09:11:53Z
html.description.abstract	The exploitation of cytochromes P450 for novel biotechnological application and for the investigation of their physiological function is of great scientific interest in this post genomic era, where an extraordinary biodiversity of P450 genes has been derived from all forms of life. The study of P450s in the myxobacterium Sorangium cellulosum strain So ce56, the producer of novel secondary metabolites of pharmaceutical interest is the research topic, in which we were engaged since the beginning of its genome sequencing project. We herein disclosed the cytochrome P450 complements (CYPomes) of spore-forming myxobacterial species, Stigmatella aurantiaca DW4/3-1, Haliangium ochraceum DSM 14365 and Myxococcus xanthus DK1622, and their potential pharmaceutical significance has been discussed.