Composing compound libraries for hit discovery--rationality-driven preselection or random choice by structural diversity?
| dc.contributor.author | Weidel, Elisabeth | |
| dc.contributor.author | Negri, Matthias | |
| dc.contributor.author | Empting, Martin | |
| dc.contributor.author | Hinsberger, Stefan | |
| dc.contributor.author | Hartmann, Rolf W | |
| dc.date.accessioned | 2015-03-02T13:39:14Z | en |
| dc.date.available | 2015-03-02T13:39:14Z | en |
| dc.date.issued | 2014 | en |
| dc.identifier.citation | Composing compound libraries for hit discovery--rationality-driven preselection or random choice by structural diversity? 2014, 6 (18):2057-72 Future Med Chem | en |
| dc.identifier.issn | 1756-8927 | en |
| dc.identifier.pmid | 25531968 | en |
| dc.identifier.doi | 10.4155/fmc.14.142 | en |
| dc.identifier.uri | http://hdl.handle.net/10033/345823 | en |
| dc.description.abstract | In order to identify new scaffolds for drug discovery, surface plasmon resonance is frequently used to screen structurally diverse libraries. Usually, hit rates are low and identification processes are time consuming. Hence, approaches which improve hit rates and, thus, reduce the library size are required. | |
| dc.language.iso | en | en |
| dc.title | Composing compound libraries for hit discovery--rationality-driven preselection or random choice by structural diversity? | en |
| dc.type | Article | en |
| dc.identifier.journal | Future medicinal chemistry | en |
| refterms.dateFOA | 2018-06-13T09:07:56Z | |
| html.description.abstract | In order to identify new scaffolds for drug discovery, surface plasmon resonance is frequently used to screen structurally diverse libraries. Usually, hit rates are low and identification processes are time consuming. Hence, approaches which improve hit rates and, thus, reduce the library size are required. |
