Soraphen A: A broad-spectrum antiviral natural product with potent anti-hepatitis C virus activity.
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Abstract
Soraphen A (SorA) is a myxobacterial metabolite that inhibits the acetyl-CoA carboxylase, a key enzyme in lipid biosynthesis. We have previously identified SorA to efficiently inhibit the human immunodeficiency virus (HIV). The aim of the present study was to evaluate the capacity of SorA and analogues to inhibit hepatitis C virus (HCV) infection.Citation
Soraphen A: A broad-spectrum antiviral natural product with potent anti-hepatitis C virus activity. 2015: J. Hepatol.Affiliation
TWINCORE, Centre for Experimental and Clinical Infection Research, Feodor-Lynen Str. 7, 30625, Hannover, Germany.Journal
Journal of hepatologyPubMed ID
26070407Type
ArticleISSN
1600-0641Scopus Count
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