Towards an advanced therapy medicinal product based on mesenchymal stromal cells isolated from the umbilical cord tissue: quality and safety data.
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Authors
Martins, José PauloSantos, Jorge Miguel
de Almeida, Joana Marto
Filipe, Mariana Alves
de Almeida, Mariana Vargas Teixeira
Almeida, Sílvia Cristina Paiva
Água-Doce, Ana
Varela, Alexandre
Gilljam, Mari
Stellan, Birgitta
Pohl, Susanne
Dittmar, Kurt
Lindenmaier, Werner
Alici, Evren
Graça, Luís
Cruz, Pedro Estilita
Cruz, Helder Joaquim
Bárcia, Rita Nogueira
Issue Date
2014
Metadata
Show full item recordAbstract
Standardization of mesenchymal stromal cells (MSCs) manufacturing is urgently needed to enable translational activities and ultimately facilitate comparison of clinical trial results. In this work we describe the adaptation of a proprietary method for isolation of a specific umbilical cord tissue-derived population of MSCs, herein designated by its registered trademark as UCX®, towards the production of an advanced therapy medicinal product (ATMP).Citation
Towards an advanced therapy medicinal product based on mesenchymal stromal cells isolated from the umbilical cord tissue: quality and safety data. 2014, 5 (1):9 Stem Cell Res TherJournal
Stem cell research & therapyDOI
10.1186/scrt398PubMed ID
24438697Type
ArticleLanguage
enISSN
1757-6512ae974a485f413a2113503eed53cd6c53
10.1186/scrt398
Scopus Count
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