Towards an advanced therapy medicinal product based on mesenchymal stromal cells isolated from the umbilical cord tissue: quality and safety data.
dc.contributor.author | Martins, José Paulo | |
dc.contributor.author | Santos, Jorge Miguel | |
dc.contributor.author | de Almeida, Joana Marto | |
dc.contributor.author | Filipe, Mariana Alves | |
dc.contributor.author | de Almeida, Mariana Vargas Teixeira | |
dc.contributor.author | Almeida, Sílvia Cristina Paiva | |
dc.contributor.author | Água-Doce, Ana | |
dc.contributor.author | Varela, Alexandre | |
dc.contributor.author | Gilljam, Mari | |
dc.contributor.author | Stellan, Birgitta | |
dc.contributor.author | Pohl, Susanne | |
dc.contributor.author | Dittmar, Kurt | |
dc.contributor.author | Lindenmaier, Werner | |
dc.contributor.author | Alici, Evren | |
dc.contributor.author | Graça, Luís | |
dc.contributor.author | Cruz, Pedro Estilita | |
dc.contributor.author | Cruz, Helder Joaquim | |
dc.contributor.author | Bárcia, Rita Nogueira | |
dc.date.accessioned | 2015-10-15T08:26:57Z | en |
dc.date.available | 2015-10-15T08:26:57Z | en |
dc.date.issued | 2014 | en |
dc.identifier.citation | Towards an advanced therapy medicinal product based on mesenchymal stromal cells isolated from the umbilical cord tissue: quality and safety data. 2014, 5 (1):9 Stem Cell Res Ther | en |
dc.identifier.issn | 1757-6512 | en |
dc.identifier.pmid | 24438697 | en |
dc.identifier.doi | 10.1186/scrt398 | en |
dc.identifier.uri | http://hdl.handle.net/10033/579735 | en |
dc.description.abstract | Standardization of mesenchymal stromal cells (MSCs) manufacturing is urgently needed to enable translational activities and ultimately facilitate comparison of clinical trial results. In this work we describe the adaptation of a proprietary method for isolation of a specific umbilical cord tissue-derived population of MSCs, herein designated by its registered trademark as UCX®, towards the production of an advanced therapy medicinal product (ATMP). | |
dc.language.iso | en | en |
dc.subject.mesh | Cells, Cultured | en |
dc.subject.mesh | Cryopreservation | en |
dc.subject.mesh | Humans | en |
dc.subject.mesh | Mesenchymal Stem Cell Transplantation | en |
dc.subject.mesh | Mesenchymal Stromal Cells | en |
dc.subject.mesh | Quality Control | en |
dc.subject.mesh | Stem Cell Research | en |
dc.subject.mesh | Tissue and Organ Harvesting | en |
dc.subject.mesh | Umbilical Cord | en |
dc.title | Towards an advanced therapy medicinal product based on mesenchymal stromal cells isolated from the umbilical cord tissue: quality and safety data. | en |
dc.type | Article | en |
dc.identifier.journal | Stem cell research & therapy | en |
refterms.dateFOA | 2018-06-13T14:17:14Z | |
html.description.abstract | Standardization of mesenchymal stromal cells (MSCs) manufacturing is urgently needed to enable translational activities and ultimately facilitate comparison of clinical trial results. In this work we describe the adaptation of a proprietary method for isolation of a specific umbilical cord tissue-derived population of MSCs, herein designated by its registered trademark as UCX®, towards the production of an advanced therapy medicinal product (ATMP). |