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dc.contributor.authorDiez, Juana
dc.contributor.authorMartinez, Javier P
dc.contributor.authorMestres, Jordi
dc.contributor.authorSasse, Florenz
dc.contributor.authorFrank, Ronald
dc.contributor.authorMeyerhans, Andreas
dc.date.accessioned2016-02-02T12:37:58Zen
dc.date.available2016-02-02T12:37:58Zen
dc.date.issued2012en
dc.identifier.citationMyxobacteria: natural pharmaceutical factories. 2012, 11:52 Microb. Cell Fact.en
dc.identifier.issn1475-2859en
dc.identifier.pmid22545867en
dc.identifier.doi10.1186/1475-2859-11-52en
dc.identifier.urihttp://hdl.handle.net/10033/595433en
dc.description.abstractMyxobacteria are amongst the top producers of natural products. The diversity and unique structural properties of their secondary metabolites is what make these social microbes highly attractive for drug discovery. Screening of products derived from these bacteria has revealed a puzzling amount of hits against infectious and non-infectious human diseases. Preying mainly on other bacteria and fungi, why would these ancient hunters manufacture compounds beneficial for us? The answer may be the targeting of shared processes and structural features conserved throughout evolution.
dc.language.isoenen
dc.relationeu-repo/grantAgreement/EC/FP7/261466en
dc.rightsopenAccessen
dc.subject.meshBiological Productsen
dc.subject.meshDrug Discoveryen
dc.subject.meshMyxococcalesen
dc.subject.meshSpores, Bacterialen
dc.titleMyxobacteria: natural pharmaceutical factories.en
dc.typeArticleen
dc.contributor.departmentHelmholtz Centre for infection research, Inhoffenstr. 7, D-38124 Braunschweig, Germany.en
dc.identifier.journalMicrobial cell factoriesen
refterms.dateFOA2018-06-12T22:06:46Z
html.description.abstractMyxobacteria are amongst the top producers of natural products. The diversity and unique structural properties of their secondary metabolites is what make these social microbes highly attractive for drug discovery. Screening of products derived from these bacteria has revealed a puzzling amount of hits against infectious and non-infectious human diseases. Preying mainly on other bacteria and fungi, why would these ancient hunters manufacture compounds beneficial for us? The answer may be the targeting of shared processes and structural features conserved throughout evolution.


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