Discovery of antiviral molecules for dengue: In silico search and biological evaluation.
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Authors
Cabarcas-Montalvo, MariaMaldonado-Rojas, Wilson
Montes-Grajales, Diana
Bertel-Sevilla, Angela
Wagner-Döbler, Irene
Sztajer, Helena
Reck, Michael
Flechas-Alarcon, Maria
Ocazionez, Raquel
Olivero-Verbel, Jesus
Issue Date
2016-03-03
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Show full item recordAbstract
Dengue disease is a global disease that has no effective treatment. The dengue virus (DENV) NS2B/NS3 protease complex is a target for designing specific antivirals due to its importance in viral replication and its high degree of conservation.Citation
Discovery of antiviral molecules for dengue: In silico search and biological evaluation. 2016, 110:87-97 Eur J Med ChemAffiliation
Helmholtz Centre for infection research, Inhoffenstr. 7, D-38124 Braunschweig, Germany.PubMed ID
26807547Type
ArticleLanguage
enISSN
1768-3254ae974a485f413a2113503eed53cd6c53
10.1016/j.ejmech.2015.12.030
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