TLR8 regulation of LILRA3 in monocytes is abrogated in human immunodeficiency virus infection and correlates to CD4 counts and virus loads.

Thumbnail
Name:
Low et al.pdf
Size:
3.702Mb
Format:
PDF
Description:
Open Access publication
Download
Cast your vote
 
Your vote was cast
Thank you for your feedback
Authors
Low, Hui Zhi
Ahrenstorf, Gerrit
Pommerenke, Claudia cc
Habermann, Nadine
Schughart, Klaus cc
Ordóñez, David
Stripecke, Renata
Wilk, Esther cc
Witte, Torsten
Issue Date
2016

Metadata
Show full item record
Abstract
LILRA3 is an immunostimulatory molecule which can conditionally induce the proliferation of cytotoxic cells. LILRA3 has a deletion genotype which is associated with multiple immune disorders. In this study, we wanted to analyze the regulation of LILRA3 and its significance in the context of HIV infection.
Citation
TLR8 regulation of LILRA3 in monocytes is abrogated in human immunodeficiency virus infection and correlates to CD4 counts and virus loads. 2016, 13 (1):15 Retrovirology
Affiliation
Department of Clinical Immunology and Rheumatology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Journal
Retrovirology
URI
http://hdl.handle.net/10033/606041
DOI
10.1186/s12977-016-0248-y
PubMed ID
26969150
Type
Article
Language
en
ISSN
1742-4690
Collections

The following license files are associated with this item: