Characterization of Microvesicles Released from Human Red Blood Cells.
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Authors
Nguyen, Duc BachThuy Ly, Thi Bich
Wesseling, Mauro Carlos
Hittinger, Marius
Torge, Afra
Devitt, Andrew
Perrie, Yvonne
Bernhardt, Ingolf
Issue Date
2016
Metadata
Show full item recordAbstract
Extracellular vesicles (EVs) are spherical fragments of cell membrane released from various cell types under physiological as well as pathological conditions. Based on their size and origin, EVs are classified as exosome, microvesicles (MVs) and apoptotic bodies. Recently, the release of MVs from human red blood cells (RBCs) under different conditions has been reported. MVs are released by outward budding and fission of the plasma membrane. However, the outward budding process itself, the release of MVs and the physical properties of these MVs have not been well investigated. The aim of this study is to investigate the formation process, isolation and characterization of MVs released from RBCs under conditions of stimulating Ca2+ uptake and activation of protein kinase C.Citation
Characterization of Microvesicles Released from Human Red Blood Cells. 2016, 38 (3):1085-99 Cell. Physiol. Biochem.Affiliation
Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS),Saarland 9 University, 66123 Saarbrücken, Germany.PubMed ID
26938586Type
ArticleLanguage
enISSN
1421-9778ae974a485f413a2113503eed53cd6c53
10.1159/000443059
Scopus Count
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