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dc.contributor.authorNguyen, Duc Bach
dc.contributor.authorThuy Ly, Thi Bich
dc.contributor.authorWesseling, Mauro Carlos
dc.contributor.authorHittinger, Marius
dc.contributor.authorTorge, Afra
dc.contributor.authorDevitt, Andrew
dc.contributor.authorPerrie, Yvonne
dc.contributor.authorBernhardt, Ingolf
dc.date.accessioned2016-05-12T14:14:28Zen
dc.date.available2016-05-12T14:14:28Zen
dc.date.issued2016en
dc.identifier.citationCharacterization of Microvesicles Released from Human Red Blood Cells. 2016, 38 (3):1085-99 Cell. Physiol. Biochem.en
dc.identifier.issn1421-9778en
dc.identifier.pmid26938586en
dc.identifier.doi10.1159/000443059en
dc.identifier.urihttp://hdl.handle.net/10033/609191en
dc.description.abstractExtracellular vesicles (EVs) are spherical fragments of cell membrane released from various cell types under physiological as well as pathological conditions. Based on their size and origin, EVs are classified as exosome, microvesicles (MVs) and apoptotic bodies. Recently, the release of MVs from human red blood cells (RBCs) under different conditions has been reported. MVs are released by outward budding and fission of the plasma membrane. However, the outward budding process itself, the release of MVs and the physical properties of these MVs have not been well investigated. The aim of this study is to investigate the formation process, isolation and characterization of MVs released from RBCs under conditions of stimulating Ca2+ uptake and activation of protein kinase C.
dc.language.isoenen
dc.titleCharacterization of Microvesicles Released from Human Red Blood Cells.en
dc.typeArticleen
dc.contributor.departmentHelmholtz-Institute for Pharmaceutical Research Saarland (HIPS),Saarland 9 University, 66123 Saarbrücken, Germany.en
dc.identifier.journalCellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacologyen
refterms.dateFOA2018-06-12T17:43:25Z
html.description.abstractExtracellular vesicles (EVs) are spherical fragments of cell membrane released from various cell types under physiological as well as pathological conditions. Based on their size and origin, EVs are classified as exosome, microvesicles (MVs) and apoptotic bodies. Recently, the release of MVs from human red blood cells (RBCs) under different conditions has been reported. MVs are released by outward budding and fission of the plasma membrane. However, the outward budding process itself, the release of MVs and the physical properties of these MVs have not been well investigated. The aim of this study is to investigate the formation process, isolation and characterization of MVs released from RBCs under conditions of stimulating Ca2+ uptake and activation of protein kinase C.


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