Structural and functional features of self-assembling protein nanoparticles produced in endotoxin-free Escherichia coli.
dc.contributor.author | Rueda, Fabián | |
dc.contributor.author | Céspedes, María Virtudes | |
dc.contributor.author | Sánchez-Chardi, Alejandro | |
dc.contributor.author | Seras-Franzoso, Joaquin | |
dc.contributor.author | Pesarrodona, Mireia | |
dc.contributor.author | Ferrer-Miralles, Neus | |
dc.contributor.author | Vázquez, Esther | |
dc.contributor.author | Rinas, Ursula | |
dc.contributor.author | Unzueta, Ugutz | |
dc.contributor.author | Mamat, Uwe | |
dc.contributor.author | Mangues, Ramón | |
dc.contributor.author | García-Fruitós, Elena | |
dc.contributor.author | Villaverde, Antonio | |
dc.date.accessioned | 2016-06-21T14:12:13Z | en |
dc.date.available | 2016-06-21T14:12:13Z | en |
dc.date.issued | 2016 | en |
dc.identifier.citation | Structural and functional features of self-assembling protein nanoparticles produced in endotoxin-free Escherichia coli. 2016, 15 (1):59 Microb. Cell Fact. | en |
dc.identifier.issn | 1475-2859 | en |
dc.identifier.pmid | 27059706 | en |
dc.identifier.doi | 10.1186/s12934-016-0457-z | en |
dc.identifier.uri | http://hdl.handle.net/10033/613872 | en |
dc.description.abstract | Production of recombinant drugs in process-friendly endotoxin-free bacterial factories targets to a lessened complexity of the purification process combined with minimized biological hazards during product application. The development of nanostructured recombinant materials in innovative nanomedical activities expands such a need beyond plain functional polypeptides to complex protein assemblies. While Escherichia coli has been recently modified for the production of endotoxin-free proteins, no data has been so far recorded regarding how the system performs in the fabrication of smart nanostructured materials. | |
dc.language.iso | en | en |
dc.title | Structural and functional features of self-assembling protein nanoparticles produced in endotoxin-free Escherichia coli. | en |
dc.type | Article | en |
dc.contributor.department | Helmholtz Centre for infection research, Inhoffenstr. 7, 38124 Braunschweig, Germany. | en |
dc.identifier.journal | Microbial cell factories | en |
refterms.dateFOA | 2018-06-12T17:21:59Z | |
html.description.abstract | Production of recombinant drugs in process-friendly endotoxin-free bacterial factories targets to a lessened complexity of the purification process combined with minimized biological hazards during product application. The development of nanostructured recombinant materials in innovative nanomedical activities expands such a need beyond plain functional polypeptides to complex protein assemblies. While Escherichia coli has been recently modified for the production of endotoxin-free proteins, no data has been so far recorded regarding how the system performs in the fabrication of smart nanostructured materials. |