The Role of Regulatory CD4 T Cells in Maintaining Tolerance in a Mouse Model of Autoimmune Hepatitis.

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Authors
An Haack, Ira
Derkow, Katja
Riehn, Mathias
Rentinck, Marc-Nicolas
Kühl, Anja A
Lehnardt, Seija
Schott, Eckart
Issue Date
2015

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Abstract
The role of regulatory CD4 T cells (Treg) in immune-mediated liver disease is still under debate. It remains disputed whether Treg suppress T cell-mediated hepatitis in vivo and whether hepatic regulatory T cells are functional in patients with autoimmune hepatitis.
Citation
The Role of Regulatory CD4 T Cells in Maintaining Tolerance in a Mouse Model of Autoimmune Hepatitis. 2015, 10 (11):e0143715 PLoS ONE
Affiliation
Dept. of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Berlin, Germany.
Journal
PloS one
URI
http://hdl.handle.net/10033/615675
DOI
10.1371/journal.pone.0143715
PubMed ID
26599014
Type
Article
Language
en
ISSN
1932-6203
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http://creativecommons.org/licenses/by-nc-sa/4.0/
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-sa/4.0/