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dc.contributor.authorCammann, Clemens
dc.contributor.authorRath, Alexander
dc.contributor.authorReichl, Udo
dc.contributor.authorLingel, Holger
dc.contributor.authorBrunner-Weinzierl, Monika
dc.contributor.authorSimeoni, Luca
dc.contributor.authorSchraven, Burkhart
dc.contributor.authorLindquist, Jonathan A
dc.date.accessioned2016-07-15T09:40:17Z
dc.date.available2016-07-15T09:40:17Z
dc.date.issued2016
dc.identifier.citationEarly changes in the metabolic profile of activated CD8(+) T cells. 2016, 17 (1):28 BMC Cell Biol.en
dc.identifier.issn1471-2121
dc.identifier.pmid27387758
dc.identifier.doi10.1186/s12860-016-0104-x
dc.identifier.urihttp://hdl.handle.net/10033/616990
dc.description.abstractAntigenic stimulation of the T cell receptor (TCR) initiates a change from a resting state into an activated one, which ultimately results in proliferation and the acquisition of effector functions. To accomplish this task, T cells require dramatic changes in metabolism. Therefore, we investigated changes of metabolic intermediates indicating for crucial metabolic pathways reflecting the status of T cells. Moreover we analyzed possible regulatory molecules required for the initiation of the metabolic changes.
dc.language.isoenen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.titleEarly changes in the metabolic profile of activated CD8(+) T cells.en
dc.typeArticleen
dc.contributor.departmentHelmholtz Centre for infection research, Inhoffenstr. 7, 38124 Braunschweig, Germany.en
dc.identifier.journalBMC cell biologyen
refterms.dateFOA2018-06-12T23:51:17Z
html.description.abstractAntigenic stimulation of the T cell receptor (TCR) initiates a change from a resting state into an activated one, which ultimately results in proliferation and the acquisition of effector functions. To accomplish this task, T cells require dramatic changes in metabolism. Therefore, we investigated changes of metabolic intermediates indicating for crucial metabolic pathways reflecting the status of T cells. Moreover we analyzed possible regulatory molecules required for the initiation of the metabolic changes.


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