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Lee et al 2016 CurrOpinMicro.pdf
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Issue Date
2016-04
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Show full item recordAbstract
Maintenance of protein homeostasis is essential for survival of all organisms. In bacteria, the protein quality control system has a broad physiological impact beyond heat shock resistance, being involved in virulence, antibiotic resistance, as well as protection against environmental stresses. Its contribution to rejuvenation and growth arrest suggests interference with protein quality control to be a novel antimicrobial strategy. Remarkably, a protein quality control module originating from environmental strains has been found to be horizontally transferred to predominant clonal groups of bacteria providing exquisite thermotolerance to recently emerged global pathogens suggesting that novel features related to protein homeostasis contribute to the transition to new environments.Citation
Protein homeostasis-more than resisting a hot bath. 2016, 30:147-54 Curr. Opin. Microbiol.Affiliation
Helmholtz Centre for infection research, Inhoffenstr. 7,38124 Braunschweig, Germany.Journal
Current opinion in microbiologyPubMed ID
26974352Type
ArticleLanguage
enISSN
1879-0364ae974a485f413a2113503eed53cd6c53
10.1016/j.mib.2016.02.006
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- Creative Commons
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-sa/4.0/
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