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dc.contributor.authorHeckl, Dirk
dc.contributor.authorCharpentier, Emmanuelle
dc.date.accessioned2016-10-19T11:01:17Z
dc.date.available2016-10-19T11:01:17Z
dc.date.issued2015-05-21
dc.identifier.citationToward Whole-Transcriptome Editing with CRISPR-Cas9. 2015, 58 (4):560-2 Mol. Cellen
dc.identifier.issn1097-4164
dc.identifier.pmid26000839
dc.identifier.doi10.1016/j.molcel.2015.05.016
dc.identifier.urihttp://hdl.handle.net/10033/620557
dc.description.abstractTargeted regulation of gene expression holds huge promise for biomedical research. In a series of recent publications (Gilbert et al., 2014; Konermann et al., 2015; Zalatan et al., 2015), sophisticated, multiplex-compatible transcriptional activator systems based on the CRISPR-Cas9 technology and genome-scale libraries advance the field toward whole-transcriptome control.
dc.languageENG
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subject.meshCRISPR-Cas Systemsen
dc.subject.meshGene Expressionen
dc.subject.meshGenetic Engineeringen
dc.subject.meshGenetic Techniquesen
dc.subject.meshGenome, Humanen
dc.subject.meshHumansen
dc.subject.meshMelanomaen
dc.subject.meshTranscription, Geneticen
dc.subject.meshTranscriptional Activationen
dc.titleToward Whole-Transcriptome Editing with CRISPR-Cas9.
dc.typeArticleen
dc.contributor.departmentHelmholtz Centre for infection research, Inhoffenstr. 7, 38124 Braunschweig, Germany.en
dc.identifier.journalMolecular cellen
refterms.dateFOA2018-06-12T23:53:41Z
html.description.abstractTargeted regulation of gene expression holds huge promise for biomedical research. In a series of recent publications (Gilbert et al., 2014; Konermann et al., 2015; Zalatan et al., 2015), sophisticated, multiplex-compatible transcriptional activator systems based on the CRISPR-Cas9 technology and genome-scale libraries advance the field toward whole-transcriptome control.


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