Toward Whole-Transcriptome Editing with CRISPR-Cas9.

Heckl, Dirk; Charpentier, Emmanuelle

dc.contributor.author	Heckl, Dirk
dc.contributor.author	Charpentier, Emmanuelle
dc.date.accessioned	2016-10-19T11:01:17Z
dc.date.available	2016-10-19T11:01:17Z
dc.date.issued	2015-05-21
dc.identifier.citation	Toward Whole-Transcriptome Editing with CRISPR-Cas9. 2015, 58 (4):560-2 Mol. Cell	en
dc.identifier.issn	1097-4164
dc.identifier.pmid	26000839
dc.identifier.doi	10.1016/j.molcel.2015.05.016
dc.identifier.uri	http://hdl.handle.net/10033/620557
dc.description.abstract	Targeted regulation of gene expression holds huge promise for biomedical research. In a series of recent publications (Gilbert et al., 2014; Konermann et al., 2015; Zalatan et al., 2015), sophisticated, multiplex-compatible transcriptional activator systems based on the CRISPR-Cas9 technology and genome-scale libraries advance the field toward whole-transcriptome control.
dc.language	ENG
dc.rights.uri	http://creativecommons.org/licenses/by-nc-sa/4.0/	*
dc.subject.mesh	CRISPR-Cas Systems	en
dc.subject.mesh	Gene Expression	en
dc.subject.mesh	Genetic Engineering	en
dc.subject.mesh	Genetic Techniques	en
dc.subject.mesh	Genome, Human	en
dc.subject.mesh	Humans	en
dc.subject.mesh	Melanoma	en
dc.subject.mesh	Transcription, Genetic	en
dc.subject.mesh	Transcriptional Activation	en
dc.title	Toward Whole-Transcriptome Editing with CRISPR-Cas9.
dc.type	Article	en
dc.contributor.department	Helmholtz Centre for infection research, Inhoffenstr. 7, 38124 Braunschweig, Germany.	en
dc.identifier.journal	Molecular cell	en
refterms.dateFOA	2018-06-12T23:53:41Z
html.description.abstract	Targeted regulation of gene expression holds huge promise for biomedical research. In a series of recent publications (Gilbert et al., 2014; Konermann et al., 2015; Zalatan et al., 2015), sophisticated, multiplex-compatible transcriptional activator systems based on the CRISPR-Cas9 technology and genome-scale libraries advance the field toward whole-transcriptome control.