A new reporter mouse cytomegalovirus reveals maintained immediate-early gene expression but poor virus replication in cycling liver sinusoidal endothelial cells.

Dag, Franziska; Weingärtner, Adrien; Butueva, Milada; Conte, Ianina; Holzki, Julia; May, Tobias; Adler, Barbara; Wirth, Dagmar; Cicin-Sain, Luka

dc.contributor.author	Dag, Franziska
dc.contributor.author	Weingärtner, Adrien
dc.contributor.author	Butueva, Milada
dc.contributor.author	Conte, Ianina
dc.contributor.author	Holzki, Julia
dc.contributor.author	May, Tobias
dc.contributor.author	Adler, Barbara
dc.contributor.author	Wirth, Dagmar
dc.contributor.author	Cicin-Sain, Luka
dc.date.accessioned	2016-11-04T14:43:44Z
dc.date.available	2016-11-04T14:43:44Z
dc.date.issued	2013-06-17
dc.identifier.citation	A new reporter mouse cytomegalovirus reveals maintained immediate-early gene expression but poor virus replication in cycling liver sinusoidal endothelial cells. 2013, 10:197 Virol. J.	en
dc.identifier.issn	1743-422X
dc.identifier.pmid	23773211
dc.identifier.doi	10.1186/1743-422X-10-197
dc.identifier.uri	http://hdl.handle.net/10033/620571
dc.description.abstract	The MCMV major immediate early promoter/enhancer (MIEP) is a bidirectional promoter that drives the expression of the three immediate early viral genes, namely ie1, ie2 and ie3. The regulation of their expression is intensively studied, but still incompletely understood.
dc.language	ENG
dc.rights.uri	http://creativecommons.org/licenses/by-nc-sa/4.0/	*
dc.subject.mesh	Animals	en
dc.subject.mesh	Artificial Gene Fusion	en
dc.subject.mesh	Cell Line	en
dc.subject.mesh	Cell Survival	en
dc.subject.mesh	Endothelial Cells	en
dc.subject.mesh	Fibroblasts	en
dc.subject.mesh	Gene Expression	en
dc.subject.mesh	Gene Expression Regulation, Viral	en
dc.subject.mesh	Genes, Immediate-Early	en
dc.subject.mesh	Genes, Reporter	en
dc.subject.mesh	Liver	en
dc.subject.mesh	Luminescent Proteins	en
dc.subject.mesh	Macrophages	en
dc.subject.mesh	Mice	en
dc.subject.mesh	Mice, Inbred BALB C	en
dc.subject.mesh	Muromegalovirus	en
dc.subject.mesh	Promoter Regions, Genetic	en
dc.subject.mesh	Single-Cell Analysis	en
dc.subject.mesh	Virus Replication	en
dc.title	A new reporter mouse cytomegalovirus reveals maintained immediate-early gene expression but poor virus replication in cycling liver sinusoidal endothelial cells.
dc.type	Article	en
dc.contributor.department	Helmholtz Centre for infection research, Inhoffenstr. 7, 38124 Braunschweig, Germany.	en
dc.identifier.journal	Virology journal	en
refterms.dateFOA	2018-06-12T18:00:04Z
html.description.abstract	The MCMV major immediate early promoter/enhancer (MIEP) is a bidirectional promoter that drives the expression of the three immediate early viral genes, namely ie1, ie2 and ie3. The regulation of their expression is intensively studied, but still incompletely understood.