Browsing publications of the research group infection genetics (INFG) by Subject (MeSH)
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Immunization with live virus vaccine protects highly susceptible DBA/2J mice from lethal influenza A H1N1 infection.The mouse represents an important model system to study the host response to influenza A infections and to evaluate new prevention or treatment strategies. We and others reported that the susceptibility to influenza A virus infections strongly varies among different inbred mouse strains. In particular, DBA/2J mice are highly susceptible to several influenza A subtypes, including human isolates and exhibit severe symptoms after infection with clinical isolates.