Browsing publications of the research group system immunology ([BRICS]SIMM) by Authors
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Novel standards in the measurement of rat insulin granules combining electron microscopy, high-content image analysis and in silico modelling.Fava, E; Dehghany, J; Ouwendijk, J; Müller, A; Niederlein, A; Verkade, P; Meyer-Hermann, M; Solimena, M; Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany. (2012-04)Knowledge of number, size and content of insulin secretory granules is pivotal for understanding the physiology of pancreatic beta cells. Here we re-evaluated key structural features of rat beta cells, including insulin granule size, number and distribution as well as cell size.