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dc.contributor.authorQuentmeier, Hilmar
dc.contributor.authorEberth, Sonja
dc.contributor.authorRomani, Julia
dc.contributor.authorWeich, Herbert A
dc.contributor.authorZaborski, Margarete
dc.contributor.authorDrexler, Hans G
dc.date.accessioned2017-02-27T11:01:09Z
dc.date.available2017-02-27T11:01:09Z
dc.date.issued2012-01-17
dc.identifier.citationDNA methylation regulates expression of VEGF-R2 (KDR) and VEGF-R3 (FLT4). 2012, 12:19 BMC Canceren
dc.identifier.issn1471-2407
dc.identifier.pmid22251800
dc.identifier.doi10.1186/1471-2407-12-19
dc.identifier.urihttp://hdl.handle.net/10033/620842
dc.description.abstractVascular Endothelial Growth Factors (VEGFs) and their receptors (VEGF-Rs) are important regulators for angiogenesis and lymphangiogenesis. VEGFs and VEGF-Rs are not only expressed on endothelial cells but also on various subtypes of solid tumors and leukemias contributing to the growth of the malignant cells. This study was performed to examine whether VEGF-R2 (KDR) and VEGF-R3 (FLT4) are regulated by DNA methylation.
dc.language.isoenen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subject.meshBlotting, Westernen
dc.subject.meshCell Line, Tumoren
dc.subject.meshDNA Methylationen
dc.subject.meshEndothelial Cellsen
dc.subject.meshGene Expression Regulationen
dc.subject.meshHuman Umbilical Vein Endothelial Cellsen
dc.subject.meshHumansen
dc.subject.meshLeukemiaen
dc.subject.meshLymphomaen
dc.subject.meshReal-Time Polymerase Chain Reactionen
dc.subject.meshSequence Analysis, DNAen
dc.subject.meshVascular Endothelial Growth Factor Receptor-2en
dc.subject.meshVascular Endothelial Growth Factor Receptor-3en
dc.titleDNA methylation regulates expression of VEGF-R2 (KDR) and VEGF-R3 (FLT4).en
dc.typeArticleen
dc.contributor.departmentHelmholtz Centre for infection research, Inhoffenstr. 7, 38124 Braunschweig, Germany.en
dc.identifier.journalBMC canceren
refterms.dateFOA2018-06-13T09:26:06Z
html.description.abstractVascular Endothelial Growth Factors (VEGFs) and their receptors (VEGF-Rs) are important regulators for angiogenesis and lymphangiogenesis. VEGFs and VEGF-Rs are not only expressed on endothelial cells but also on various subtypes of solid tumors and leukemias contributing to the growth of the malignant cells. This study was performed to examine whether VEGF-R2 (KDR) and VEGF-R3 (FLT4) are regulated by DNA methylation.


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