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dc.contributor.authorHacquard, Stéphane
dc.contributor.authorKracher, Barbara
dc.contributor.authorHiruma, Kei
dc.contributor.authorMünch, Philipp C
dc.contributor.authorGarrido-Oter, Ruben
dc.contributor.authorThon, Michael R
dc.contributor.authorWeimann, Aaron
dc.contributor.authorDamm, Ulrike
dc.contributor.authorDallery, Jean-Félix
dc.contributor.authorHainaut, Matthieu
dc.contributor.authorHenrissat, Bernard
dc.contributor.authorLespinet, Olivier
dc.contributor.authorSacristán, Soledad
dc.contributor.authorVer Loren van Themaat, Emiel
dc.contributor.authorKemen, Eric
dc.contributor.authorMcHardy, Alice Carolyn
dc.contributor.authorSchulze-Lefert, Paul
dc.contributor.authorO'Connell, Richard J
dc.date.accessioned2017-05-05T09:02:33Z
dc.date.available2017-05-05T09:02:33Z
dc.date.issued2016-05-06
dc.identifier.citationSurvival trade-offs in plant roots during colonization by closely related beneficial and pathogenic fungi. 2016, 7:11362 Nat Communen
dc.identifier.issn2041-1723
dc.identifier.pmid27150427
dc.identifier.doi10.1038/ncomms11362
dc.identifier.urihttp://hdl.handle.net/10033/620909
dc.description.abstractThe sessile nature of plants forced them to evolve mechanisms to prioritize their responses to simultaneous stresses, including colonization by microbes or nutrient starvation. Here, we compare the genomes of a beneficial root endophyte, Colletotrichum tofieldiae and its pathogenic relative C. incanum, and examine the transcriptomes of both fungi and their plant host Arabidopsis during phosphate starvation. Although the two species diverged only 8.8 million years ago and have similar gene arsenals, we identify genomic signatures indicative of an evolutionary transition from pathogenic to beneficial lifestyles, including a narrowed repertoire of secreted effector proteins, expanded families of chitin-binding and secondary metabolism-related proteins, and limited activation of pathogenicity-related genes in planta. We show that beneficial responses are prioritized in C. tofieldiae-colonized roots under phosphate-deficient conditions, whereas defense responses are activated under phosphate-sufficient conditions. These immune responses are retained in phosphate-starved roots colonized by pathogenic C. incanum, illustrating the ability of plants to maximize survival in response to conflicting stresses.
dc.language.isoenen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.titleSurvival trade-offs in plant roots during colonization by closely related beneficial and pathogenic fungi.en
dc.typeArticleen
dc.contributor.departmentBRICS, Braunschweiger Zentrum für Systembiologie, Rebenring 56, 38106 Braunschweig, Germany.en
dc.identifier.journalNature communicationsen
refterms.dateFOA2018-06-02T16:44:58Z
html.description.abstractThe sessile nature of plants forced them to evolve mechanisms to prioritize their responses to simultaneous stresses, including colonization by microbes or nutrient starvation. Here, we compare the genomes of a beneficial root endophyte, Colletotrichum tofieldiae and its pathogenic relative C. incanum, and examine the transcriptomes of both fungi and their plant host Arabidopsis during phosphate starvation. Although the two species diverged only 8.8 million years ago and have similar gene arsenals, we identify genomic signatures indicative of an evolutionary transition from pathogenic to beneficial lifestyles, including a narrowed repertoire of secreted effector proteins, expanded families of chitin-binding and secondary metabolism-related proteins, and limited activation of pathogenicity-related genes in planta. We show that beneficial responses are prioritized in C. tofieldiae-colonized roots under phosphate-deficient conditions, whereas defense responses are activated under phosphate-sufficient conditions. These immune responses are retained in phosphate-starved roots colonized by pathogenic C. incanum, illustrating the ability of plants to maximize survival in response to conflicting stresses.


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