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dc.contributor.authorKhanam, Arshi
dc.contributor.authorTrehanpati, Nirupma
dc.contributor.authorRiese, Peggy
dc.contributor.authorRastogi, Archana
dc.contributor.authorGuzman, Carlos A.
dc.contributor.authorSarin, Shiv Kumar
dc.date.accessioned2017-05-17T12:07:22Z
dc.date.available2017-05-17T12:07:22Z
dc.date.issued2017
dc.identifier.citationBlockade of Neutrophil's Chemokine Receptors CXCR1/2 Abrogate Liver Damage in Acute-on-Chronic Liver Failure. 2017, 8:464 Front Immunolen
dc.identifier.pmid28484461
dc.identifier.doi10.3389/fimmu.2017.00464
dc.identifier.urihttp://hdl.handle.net/10033/620921
dc.description.abstractNeutrophils serve as critical players in the pathogenesis of liver diseases. Chemokine receptors CXCR1 and CXCR2 are required for neutrophil chemotaxis to the site of inflammation/injury and are crucial in hepatic inflammatory response. However, key mechanism of neutrophil-mediated liver injury in acute-on-chronic liver failure (ACLF) remains highly elusive; which could be targeted for the development of new therapeutic interventions.
dc.language.isoenen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.titleBlockade of Neutrophil's Chemokine Receptors CXCR1/2 Abrogate Liver Damage in Acute-on-Chronic Liver Failure.en
dc.typeArticleen
dc.contributor.departmentHelmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7, 38124 Braunschweig, Germany.en
dc.identifier.journalFrontiers in immunologyen
refterms.dateFOA2018-06-13T03:52:26Z
html.description.abstractNeutrophils serve as critical players in the pathogenesis of liver diseases. Chemokine receptors CXCR1 and CXCR2 are required for neutrophil chemotaxis to the site of inflammation/injury and are crucial in hepatic inflammatory response. However, key mechanism of neutrophil-mediated liver injury in acute-on-chronic liver failure (ACLF) remains highly elusive; which could be targeted for the development of new therapeutic interventions.


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