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dc.contributor.authorNickel, Sabrina
dc.contributor.authorSelo, Mohammed Ali
dc.contributor.authorFallack, Juliane
dc.contributor.authorClerkin, Caoimhe G
dc.contributor.authorHuwer, Hanno
dc.contributor.authorSchneider-Daum, Nicole
dc.contributor.authorLehr, Claus Michael
dc.contributor.authorEhrhardt, Carsten
dc.date.accessioned2017-05-22T11:54:26Z
dc.date.available2017-05-22T11:54:26Z
dc.date.issued2017-05-03
dc.identifier.citationExpression and Activity of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Distal Lung Epithelial Cells In Vitro. 2017 Pharm. Res.en
dc.identifier.issn1573-904X
dc.identifier.pmid28470471
dc.identifier.doi10.1007/s11095-017-2172-9
dc.identifier.urihttp://hdl.handle.net/10033/620926
dc.description.abstractBreast cancer resistance protein (BCRP/ABCG2) has previously been identified with high expression levels in human lung. The subcellular localisation and functional activity of the transporter in lung epithelia, however, remains poorly investigated. The aim of this project was to study BCRP expression and activity in freshly isolated human alveolar epithelial type 2 (AT2) and type 1-like (AT1-like) cells in primary culture, and to compare these findings with data obtained from the NCI-H441 cell line.
dc.language.isoenen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.titleExpression and Activity of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Distal Lung Epithelial Cells In Vitro.en
dc.typeArticleen
dc.contributor.departmentHelmholtz Institut für Pharmaceutischr Forschung Saarland, Universitätscampus E8.1, 66123 Saarbrücken, Germany.en
dc.identifier.journalPharmaceutical researchen
refterms.dateFOA2018-05-05T00:00:00Z
html.description.abstractBreast cancer resistance protein (BCRP/ABCG2) has previously been identified with high expression levels in human lung. The subcellular localisation and functional activity of the transporter in lung epithelia, however, remains poorly investigated. The aim of this project was to study BCRP expression and activity in freshly isolated human alveolar epithelial type 2 (AT2) and type 1-like (AT1-like) cells in primary culture, and to compare these findings with data obtained from the NCI-H441 cell line.


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