Assessment of an APOBEC3B truncating mutation, c.783delG, in patients with breast cancer.

Thumbnail
Name:
Manuscript APOBEC3B revised.pdf
Size:
129.3Kb
Format:
PDF
Description:
original manuscript
Download
Thumbnail
Name:
Table 1 revised.pdf
Size:
117.8Kb
Format:
PDF
Description:
Table 1
Download
Cast your vote
 
Your vote was cast
Thank you for your feedback
Authors
Radmanesh, Hoda
Spethmann, Tessa
Enßen, Julia
Schürmann, Peter
Bhuju, Sabin
Geffers, Robert cc
Antonenkova, Natalia
Khusnutdinova, Elza
Sadr-Nabavi, Ariane
Shandiz, Fatemeh Homaei
Issue Date
2017-02

Metadata
Show full item record
Abstract
APOBEC3B belongs to the family of DNA-editing enzymes. A copy number variant targeting the genomic APOBEC3A-APOBEC3B locus has a significant impact on breast cancer risk, but the relative contribution of APOBEC3B is uncertain. In this study, we investigate a loss-of-function mutation that selectively targets APOBEC3B, for its association with breast cancer risk.
Citation
Assessment of an APOBEC3B truncating mutation, c.783delG, in patients with breast cancer. 2017, 162 (1):31-37 Breast Cancer Res. Treat.
Affiliation
Helmholtz Centre for infection research, Inhoffenstr.7, 38124 Braunschweig, Germany.
Journal
Breast cancer research and treatment
URI
http://hdl.handle.net/10033/620962
DOI
10.1007/s10549-016-4100-9
PubMed ID
28062980
Type
Article
Language
en
ISSN
1573-7217
Collections

The following license files are associated with this item:

  • Creative Commons
http://creativecommons.org/licenses/by-nc-sa/4.0/
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-sa/4.0/