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Assessment of an APOBEC3B truncating mutation, c.783delG, in patients with breast cancer.

dc.contributor.authorRadmanesh, Hoda
dc.contributor.authorSpethmann, Tessa
dc.contributor.authorEnßen, Julia
dc.contributor.authorSchürmann, Peter
dc.contributor.authorBhuju, Sabin
dc.contributor.authorGeffers, Robert
dc.contributor.authorAntonenkova, Natalia
dc.contributor.authorKhusnutdinova, Elza
dc.contributor.authorSadr-Nabavi, Ariane
dc.contributor.authorShandiz, Fatemeh Homaei
dc.contributor.authorPark-Simon, Tjoung-Won
dc.contributor.authorHillemanns, Peter
dc.contributor.authorChristiansen, Hans
dc.contributor.authorBogdanova, Natalia
dc.contributor.authorDörk, Thilo
dc.date.accessioned2017-06-20T11:43:15Z
dc.date.available2017-06-20T11:43:15Z
dc.date.issued2017-02
dc.identifier.citationAssessment of an APOBEC3B truncating mutation, c.783delG, in patients with breast cancer. 2017, 162 (1):31-37 Breast Cancer Res. Treat.en
dc.identifier.issn1573-7217
dc.identifier.pmid28062980
dc.identifier.doi10.1007/s10549-016-4100-9
dc.identifier.urihttp://hdl.handle.net/10033/620962
dc.description.abstractAPOBEC3B belongs to the family of DNA-editing enzymes. A copy number variant targeting the genomic APOBEC3A-APOBEC3B locus has a significant impact on breast cancer risk, but the relative contribution of APOBEC3B is uncertain. In this study, we investigate a loss-of-function mutation that selectively targets APOBEC3B, for its association with breast cancer risk.
dc.language.isoenen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.titleAssessment of an APOBEC3B truncating mutation, c.783delG, in patients with breast cancer.en
dc.typeArticleen
dc.contributor.departmentHelmholtz Centre for infection research, Inhoffenstr.7, 38124 Braunschweig, Germany.en
dc.identifier.journalBreast cancer research and treatmenten
refterms.dateFOA2018-02-01T00:00:00Z
html.description.abstractAPOBEC3B belongs to the family of DNA-editing enzymes. A copy number variant targeting the genomic APOBEC3A-APOBEC3B locus has a significant impact on breast cancer risk, but the relative contribution of APOBEC3B is uncertain. In this study, we investigate a loss-of-function mutation that selectively targets APOBEC3B, for its association with breast cancer risk.


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