Browsing Division of RNA biology of bacterial infections ([HIRI] RABI) by Subjects
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Humanized mice for modeling human infectious disease: challenges, progress, and outlook.Over 800 million people worldwide are infected with hepatitis viruses, human immunodeficiency virus (HIV), and malaria, resulting in more than 5 million deaths annually. Here we discuss the potential and challenges of humanized mouse models for developing effective and affordable therapies and vaccines, which are desperately needed to combat these diseases.