Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses.

Siddharta, Anindya; Pfaender, Stephanie; Vielle, Nathalie Jane; Dijkman, Ronald; Friesland, Martina; Becker, Britta; Yang, Jaewon; Engelmann, Michael; Todt, Daniel; Windisch, Marc P; Brill, Florian H; Steinmann, Joerg; Steinmann, Jochen; Becker, Stephan; Alves, Marco P; Pietschmann, Thomas; Eickmann, Markus; Thiel, Volker; Steinmann, Eike

dc.contributor.author	Siddharta, Anindya
dc.contributor.author	Pfaender, Stephanie
dc.contributor.author	Vielle, Nathalie Jane
dc.contributor.author	Dijkman, Ronald
dc.contributor.author	Friesland, Martina
dc.contributor.author	Becker, Britta
dc.contributor.author	Yang, Jaewon
dc.contributor.author	Engelmann, Michael
dc.contributor.author	Todt, Daniel
dc.contributor.author	Windisch, Marc P
dc.contributor.author	Brill, Florian H
dc.contributor.author	Steinmann, Joerg
dc.contributor.author	Steinmann, Jochen
dc.contributor.author	Becker, Stephan
dc.contributor.author	Alves, Marco P
dc.contributor.author	Pietschmann, Thomas
dc.contributor.author	Eickmann, Markus
dc.contributor.author	Thiel, Volker
dc.contributor.author	Steinmann, Eike
dc.date.accessioned	2017-06-22T09:40:09Z
dc.date.available	2017-06-22T09:40:09Z
dc.date.issued	2017-03-15
dc.identifier.citation	Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses. 2017, 215 (6):902-906 J. Infect. Dis.	en
dc.identifier.issn	1537-6613
dc.identifier.pmid	28453839
dc.identifier.doi	10.1093/infdis/jix046
dc.identifier.uri	http://hdl.handle.net/10033/620973
dc.description.abstract	The World Health Organization (WHO) published 2 alcohol-based formulations to be used in healthcare settings and for outbreak-associated infections, but inactivation efficacies of these products have not been determined against (re-)emerging viruses. In this study, we evaluated the virucidal activity of these WHO products in a comparative analysis. Zika virus (ZIKV), Ebola virus (EBOV), severe acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (MERS-CoV) as (re-)emerging viral pathogens and other enveloped viruses could be efficiently inactivated by both WHO formulations, implicating their use in healthcare systems and viral outbreak situations.
dc.language.iso	en	en
dc.rights.uri	http://creativecommons.org/licenses/by-nc-sa/4.0/	*
dc.title	Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses.	en
dc.type	Article	en
dc.contributor.department	TWINCORE, Zentrum für experimentelle und klinische Infektionsforschung gmbH, Feodor-Lynen Str. 7, 30625 Hannover, Germany.	en
dc.identifier.journal	The Journal of infectious diseases	en
refterms.dateFOA	2018-06-12T16:52:37Z
html.description.abstract	The World Health Organization (WHO) published 2 alcohol-based formulations to be used in healthcare settings and for outbreak-associated infections, but inactivation efficacies of these products have not been determined against (re-)emerging viruses. In this study, we evaluated the virucidal activity of these WHO products in a comparative analysis. Zika virus (ZIKV), Ebola virus (EBOV), severe acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (MERS-CoV) as (re-)emerging viral pathogens and other enveloped viruses could be efficiently inactivated by both WHO formulations, implicating their use in healthcare systems and viral outbreak situations.