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Humanized mice for modeling human infectious disease: challenges, progress, and outlook.

dc.contributor.authorLegrand, Nicolas
dc.contributor.authorPloss, Alexander
dc.contributor.authorBalling, Rudi
dc.contributor.authorBecker, Pablo D
dc.contributor.authorBorsotti, Chiara
dc.contributor.authorBrezillon, Nicolas
dc.contributor.authorDebarry, Jennifer
dc.contributor.authorde Jong, Ype
dc.contributor.authorDeng, Hongkui
dc.contributor.authorDi Santo, James P
dc.contributor.authorEisenbarth, Stephanie
dc.contributor.authorEynon, Elizabeth
dc.contributor.authorFlavell, Richard A
dc.contributor.authorGuzman, Carlos A
dc.contributor.authorHuntington, Nicholas D
dc.contributor.authorKremsdorf, Dina
dc.contributor.authorManns, Michael P
dc.contributor.authorManz, Markus G
dc.contributor.authorMention, Jean-Jacques
dc.contributor.authorOtt, Michael
dc.contributor.authorRathinam, Chozhavendan
dc.contributor.authorRice, Charles M
dc.contributor.authorRongvaux, Anthony
dc.contributor.authorStevens, Sean
dc.contributor.authorSpits, Hergen
dc.contributor.authorStrick-Marchand, Hélène
dc.contributor.authorTakizawa, Hitoshi
dc.contributor.authorvan Lent, Anja U
dc.contributor.authorWang, Chengyan
dc.contributor.authorWeijer, Kees
dc.contributor.authorWillinger, Tim
dc.contributor.authorZiegler, Patrick
dc.date.accessioned2017-07-25T10:31:53Z
dc.date.available2017-07-25T10:31:53Z
dc.date.issued2009-07-23
dc.identifier.citationHumanized mice for modeling human infectious disease: challenges, progress, and outlook. 2009, 6 (1):5-9 Cell Host Microbeen
dc.identifier.issn1934-6069
dc.identifier.pmid19616761
dc.identifier.doi10.1016/j.chom.2009.06.006
dc.identifier.urihttp://hdl.handle.net/10033/621017
dc.description.abstractOver 800 million people worldwide are infected with hepatitis viruses, human immunodeficiency virus (HIV), and malaria, resulting in more than 5 million deaths annually. Here we discuss the potential and challenges of humanized mouse models for developing effective and affordable therapies and vaccines, which are desperately needed to combat these diseases.
dc.language.isoenen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subject.meshAnimalsen
dc.subject.meshBiomedical Researchen
dc.subject.meshCommunicable Diseasesen
dc.subject.meshDisease Models, Animalen
dc.subject.meshHumansen
dc.subject.meshMiceen
dc.titleHumanized mice for modeling human infectious disease: challenges, progress, and outlook.en
dc.typeArticleen
dc.identifier.journalCell host & microbeen
refterms.dateFOA2018-06-13T00:22:57Z
html.description.abstractOver 800 million people worldwide are infected with hepatitis viruses, human immunodeficiency virus (HIV), and malaria, resulting in more than 5 million deaths annually. Here we discuss the potential and challenges of humanized mouse models for developing effective and affordable therapies and vaccines, which are desperately needed to combat these diseases.


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