Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties.
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Authors
Prajeeth, Chittappen KKronisch, Julius
Khorooshi, Reza
Knier, Benjamin
Toft-Hansen, Henrik
Gudi, Viktoria
Floess, Stefan
Huehn, Jochen
Owens, Trevor
Korn, Thomas
Stangel, Martin
Issue Date
2017-10-16
Metadata
Show full item recordAbstract
Autoreactive Th1 and Th17 cells are believed to mediate the pathology of multiple sclerosis in the central nervous system (CNS). Their interaction with microglia and astrocytes in the CNS is crucial for the regulation of the neuroinflammation. Previously, we have shown that only Th1 but not Th17 effectors activate microglia. However, it is not clear which cells are targets of Th17 effectors in the CNS.Citation
Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties. 2017, 14 (1):204 J NeuroinflammationAffiliation
Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7, 38124 Braunschweig, Germany.Journal
Journal of neuroinflammationPubMed ID
29037246Type
ArticleLanguage
enISSN
1742-2094ae974a485f413a2113503eed53cd6c53
10.1186/s12974-017-0978-3
Scopus Count
The following license files are associated with this item:
- Creative Commons
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-sa/4.0/
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