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Partial verification bias and incorporation bias affected accuracy estimates of diagnostic studies for biomarkers that were part of an existing composite gold standard.

dc.contributor.authorKarch, Annika
dc.contributor.authorKoch, Armin
dc.contributor.authorZapf, Antonia
dc.contributor.authorZerr, Inga
dc.contributor.authorKarch, André
dc.date.accessioned2018-03-12T15:04:42Z
dc.date.available2018-03-12T15:04:42Z
dc.date.issued2016-10
dc.identifier.citationPartial verification bias and incorporation bias affected accuracy estimates of diagnostic studies for biomarkers that were part of an existing composite gold standard. 2016, 78:73-82 J Clin Epidemiolen
dc.identifier.issn1878-5921
dc.identifier.pmid27107877
dc.identifier.doi10.1016/j.jclinepi.2016.03.022
dc.identifier.urihttp://hdl.handle.net/10033/621320
dc.description.abstractTo investigate how choice of gold standard biases estimates of sensitivity and specificity in studies reassessing the diagnostic accuracy of biomarkers that are already part of a lifetime composite gold standard (CGS).
dc.language.isoenen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subject.meshAutopsyen
dc.subject.meshBiasen
dc.subject.meshBiomarkersen
dc.subject.meshComputer Simulationen
dc.subject.meshCreutzfeldt-Jakob Syndromeen
dc.subject.meshDiagnostic Tests, Routineen
dc.subject.meshHumansen
dc.subject.meshReference Standardsen
dc.subject.meshReproducibility of Resultsen
dc.subject.meshSensitivity and Specificityen
dc.titlePartial verification bias and incorporation bias affected accuracy estimates of diagnostic studies for biomarkers that were part of an existing composite gold standard.en
dc.typeArticleen
dc.contributor.departmentHelmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7, 38124 Braunschweig, Germany.en
dc.identifier.journalJournal of clinical epidemiologyen
refterms.dateFOA2018-06-13T00:02:35Z
html.description.abstractTo investigate how choice of gold standard biases estimates of sensitivity and specificity in studies reassessing the diagnostic accuracy of biomarkers that are already part of a lifetime composite gold standard (CGS).


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