Homologous recombination mediates stable Fah gene integration and phenotypic correction in tyrosinaemia mouse-model.

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Authors
Junge, Norman
Yuan, Qinggong
Vu, Thu Huong
Krooss, Simon
Bednarski, Christien
Balakrishnan, Asha
Cathomen, Toni
Manns, Michael P cc
Baumann, Ulrich
Sharma, Amar Deep
Issue Date
2018-02-27

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Abstract
To stably correct tyrosinaemia in proliferating livers of fumarylacetoacetate-hydrolase knockout (Fah-/-)mice by homologous-recombination-mediated targeted addition of theFahgene.
Citation
Homologous recombination mediates stable Fah gene integration and phenotypic correction in tyrosinaemia mouse-model. 2018, 10 (2):277-286 World J Hepatol
Affiliation
TWINCORE, Zentrum für experimentelle und klinischeInfektionsforschung GmbH, Feodor-Lynen-Str. 7, 30625 Hannover, Germany.
Journal
World journal of hepatology
URI
http://hdl.handle.net/10033/621336
DOI
10.4254/wjh.v10.i2.277
PubMed ID
29527263
Type
Article
Language
en
ISSN
1948-5182
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http://creativecommons.org/licenses/by-nc-sa/4.0/
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-sa/4.0/