Identification and Characterization of T5-Like Bacteriophages Representing Two Novel Subgroups from Food Products.
Average rating
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Star rating
Your vote was cast
Thank you for your feedback
Thank you for your feedback
Issue Date
2018
Metadata
Show full item recordAbstract
During recent years, interest in the use of bacteriophages as biocontrol agents against foodborne pathogens has increased, particularly for members of the family Enterobacteriaceae, with pathogenic Escherichia coli, Shigella, and Salmonella strains among them. Here, we report the isolation and characterisation of 12 novel T5-like bacteriophages from confiscated food samples. All bacterophages effectively lysed E. coli K-12 strains and were able to infect pathogenic E. coli strains representing enterohaemorrhagic (EHEC), enteropathogenic (EPEC), enterotoxigenic (ETEC), and enteroinvasive (EIEC) pathotypes, Shigella dysenteriae, S. sonnei strains, as well as multidrug-resistant (MDR) E. coli and multiple strains representing different Salmonella enterica serovars. All the bacteriophages exhibited Siphoviridae morphology. Whole genome sequencing of the novel T5-like bacteriophages showed that they represent two distinct groups, with the genome-based grouping correlating to the different host spectra. As these bacteriophages are of food origin, their stability and lack of any virulence genes, as well as their broad and mutually complementary host spectrum makes these new T5-like bacteriophages valuable candidates for use as biocontrol agents against foodborne pathogenic enterobacteria.Citation
Identification and Characterization of T5-Like Bacteriophages Representing Two Novel Subgroups from Food Products. 2018, 9:202 Front MicrobiolAffiliation
Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7, 38124 Braunschweig, Germany.Journal
Frontiers in microbiologyPubMed ID
29487585Type
ArticleLanguage
enISSN
1664-302Xae974a485f413a2113503eed53cd6c53
10.3389/fmicb.2018.00202
Scopus Count
The following license files are associated with this item:
- Creative Commons
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-sa/4.0/
Related articles
- Identification and characterization of new broad host-range rV5-like coliphages C203 and P206 directed against enterobacteria.
- Authors: Sváb D, Falgenhauer L, Rohde M, Chakraborty T, Tóth I
- Issue date: 2018 Oct
- Evolutionary relationships among pathogenic and nonpathogenic Escherichia coli strains inferred from multilocus enzyme electrophoresis and mdh sequence studies.
- Authors: Pupo GM, Karaolis DK, Lan R, Reeves PR
- Issue date: 1997 Jul
- Application of BI-EHEC and BI-EPEC bacteriophages to control enterohemorrhagic and enteropathogenic escherichia coli on various food surfaces.
- Authors: L A LA, Waturangi DE
- Issue date: 2023 Jun 13
- Isolation and characterization of bacteriophages from soil against food spoilage and foodborne pathogenic bacteria.
- Authors: Artawinata PC, Lorraine S, Waturangi DE
- Issue date: 2023 Jun 7
- Isolation and characterization of polyvalent bacteriophages infecting multi drug resistant Salmonella serovars isolated from broilers in Egypt.
- Authors: Mahmoud M, Askora A, Barakat AB, Rabie OE, Hassan SE
- Issue date: 2018 Feb 2