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dc.contributor.authorSchneider, Kai Markus
dc.contributor.authorWirtz, Theresa H
dc.contributor.authorKroy, Daniela
dc.contributor.authorAlbers, Stefanie
dc.contributor.authorNeumann, Ulf Peter
dc.contributor.authorStrowig, Till
dc.contributor.authorSellge, Gernot
dc.contributor.authorTrautwein, Christian
dc.date.accessioned2018-05-18T11:41:56Z
dc.date.available2018-05-18T11:41:56Z
dc.date.issued2018-05-18
dc.identifier.citationSuccessful Fecal Microbiota Transplantation in a Patient with Severe Complicated Clostridium difficile Infection after Liver Transplantation., 12 (1):76-84 Case Rep Gastroenterolen
dc.identifier.issn1662-0631
dc.identifier.pmid29606940
dc.identifier.doi10.1159/000481937
dc.identifier.urihttp://hdl.handle.net/10033/621374
dc.description.abstractClostridium difficile infection (CDI) represents one of the most common healthcare-associated infections. Due to increasing numbers of recurrences and therapy failures, CDI has become a major disease burden. Studies have shown that fecal microbiota transplantation (FMT) can both be a safe and highly efficacious therapy for patients with therapy-refractory CDI. However, patients undergoing solid organ transplantation are at high risk for CDI due to long-term immunosuppression, previous antibiotic therapy, and proton pump inhibitor use. Additionally, these patients may be especially prone to adverse events related to FMT. Here, we report a successful FMT in a patient with severe therapy-refractory CDI after liver transplantation.
dc.language.isoenen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.titleSuccessful Fecal Microbiota Transplantation in a Patient with Severe Complicated Clostridium difficile Infection after Liver Transplantation.en
dc.typeArticleen
dc.contributor.departmentHelmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7, 38124 Braunschweig, Germany.en
dc.identifier.journalCase reports in gastroenterologyen
refterms.dateFOA2018-06-13T00:27:22Z
html.description.abstractClostridium difficile infection (CDI) represents one of the most common healthcare-associated infections. Due to increasing numbers of recurrences and therapy failures, CDI has become a major disease burden. Studies have shown that fecal microbiota transplantation (FMT) can both be a safe and highly efficacious therapy for patients with therapy-refractory CDI. However, patients undergoing solid organ transplantation are at high risk for CDI due to long-term immunosuppression, previous antibiotic therapy, and proton pump inhibitor use. Additionally, these patients may be especially prone to adverse events related to FMT. Here, we report a successful FMT in a patient with severe therapy-refractory CDI after liver transplantation.


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